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Cytotoxic Activity and Apoptosis Induction of Hypericum scabrum L.
Traditional Medicine Caspase-3 Apoptosis Annexin V Protein
2015/11/9
Background: One of the acquired biological hallmarks of tumor multistep development is the resistance of cancer cells to apoptosis; therefore, induction of apoptosis is an important therapeutic approa...
Immunological Tolerance: Therapeutic Induction
免疫耐受诱导 Immunological Tolerance: Therapeutic Induction
2014/6/24
Protection from the development of autoimmune diseases and acceptance of transplanted organs are due to effective tolerance to self-antigens and alloantigens, respectively. Various immunological strat...
Challenges on Induction of Broadly Neutralizing Antibodies for Optimization of HIV Vaccines Development and Vectored Immunoprophylaxis
HIV AIDS Broadly Neutralizing Antibodies (bNAbs) Vectored Immunoprophylaxis
2013/1/30
Despite extensive research efforts, a preventive human immunodeficiency virus (HIV) vaccine remains one of the major challenges in the field of AIDS research. Experimental strategies which have been p...
The Comparison of the Effect of Three Anesthetic Induction Regimens on the Arterial Oxygen Saturation in Children with Tetralogy of Fallot Undergoing Cardiac Surgery
Tetralogy of fallot SaO2% Halothane Ketamine
2015/9/24
Background: Tetralogy of fallot (TOF) is the most common cyanotic congenital heart disease. Anesthesia induction is a challenging issue in these patients due to the risk of worsening hypoxemia followi...
Amphiregulin is Not Essential for Induction of Contact Hypersensitivity
amphiregulin contact dermatitis EGF mast cells Th2 cell/cytokine
2010/11/12
Background: Amphiregulin (AR) is expressed in Th2 cells, rather than Th1 cells, and plays an important role in Th2 cell/cytokine-mediated host defense against nematodes. We also found earlier that AR ...
Schistosome eggs have a direct role in the induction of basophils capable of a high level of IL-4 production: Comparative study of single- and bisexual infection of Schistosoma mansoni in vivo
Schsitosoma mansoni Immunoregulation
2010/12/10
Immunobiological roles of schistosome eggs during murine experimental infection were investigated with special reference to the induction of basophilic leukocytes. After single- or bisexual infection ...
Rush Specific Oral Tolerance Induction in School-Age Children with Severe Egg Allergy: One Year Follow Up
egg allergy food allergy immunotherapy oral tolerance rush
2010/11/12
Background: At present, the only treatment for food allergy is to avoid the allergy-causing food. Some trials of specific oral tolerance induction (SOTI) have been carried out, but the rate of toleran...
A new approach for the induction of vitiligo in mice
Mushroom tyrosinase Human vitiligo Experimental autoimmune vitiligo
2009/12/28
Tyrosinase has been recognized as a major autoantign in human vitiligo. Here we have shown that experimental autoimmune vitiligo can be induced by intradermal injection of mushroom tyrosinase emulsifi...
A comparison of vaginal Misoprostol with intravenous Oxytocin for cervical ripening and labor induction
Misoprostol Oxytocin Ripening
2009/12/24
Labor induction despite an unriped cervix is one of the most common indications of the use of prostaglandines. This clinical trial was performed to compare the effectiveness of oxytocin with misoprost...
Maternal serum Dehydroepiandrosterone Sulfate levels and successful labor induction
Maternal serum dehydroepiandrosterone sulfate Labor induction
2009/12/24
To evaluate the maternal serum dehydroepiandrosterone sulfate level as a factor associated with the outcome of labor induction. Venous blood was collected from 45 women at the initiation of labor indu...
Local Induction of a Specific Th1 Immune Response by Allergen Linked Immunostimulatory DNA in the Nasal Explants of Ragweed-Allergic Subjects
allergen allergic rhinitis CpG motif immunotherapy vaccination
2010/11/16
RW or Amb-a-1 increased the number of IL-4, IL-5, and IL-13 mRNA+ cells in the tissue compared to medium alone. AIC had similar cytokine mRNA reactivity as control tissue. AIC and TT increased IFNγ-mR...
Tolerance Induction by CD40 Silenced Dendritic Cells through Antisense
Dendritic cell Antisense CD40 Tolerance induction
2015/9/18
Background: One of the valuable tools for inhibiting the specific gene expression is antisense technique. To determine T cell responses, co-stimulatory molecule expression on the antigen presenting ce...
Comparing the Combination Effect of Propofol-Ketamine and Propofol-Alfentanil on Hemodynamic Stability during Induction of General Anesthesia in the Elderly
Propofol Ketamine Alfentanil Hemodynamic stability General anesthesia
2015/9/18
Background: Propofol (Diprivan), a modern intravenous hypnotic drug, produces a reduction in both cardiac index (CI) and mean arterial pressure (MAP) due to its sympatholytic activity. S-Ketamine (Ket...
Induction of apoptosis in human bladder cancer cells by green tea catechins
apoptosis human bladder cancer cells
2009/12/16
Cell culture and animal studies have demonstrated strong chemopreventative effects of green tea and its associated polyphenols in multiple cancers, though the exact mechanisms of action are not well u...
In vivo and in vitro induction of cytochrome P-450 synthesis in hyperoxia
animal mice Cytochrome P-450 Dark Adaptation Light Adaptation
2009/7/17
Exposure of dark- or light-adapted mice to 1--3 ATA oxygen for times ranging from 15 min to 4 h caused a progressive increase in P-450, which peaked and then decayed. The rate of decay appears to be i...