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The simple fool’s guide to population genomics via RNA-Seq: an introduction to high-throughput sequencing data analysis
bioinformatics de novo assembly gene expression
2015/12/11
High-throughput sequencing technologies are currently revolutionizing the field of biology and medicine, yet bioinformatic challenges in analysing very large data sets have slowed the adoption o...
How to study the mind: An introduction to embodied cognition
Embodied cognition biological environment evolution biology
2015/7/31
Embodied Cognition (EC) is a comprehensive approach to, and framework for, the study of the mind. EC treats cognition as a coordinated set of tools evolved by organisms for coping with their environme...
Evolution and Mirror Neurons. An Introduction to the Nature of Self-Consciousness
self-awareness self-consciousness evolution mirror neuron non human primate intersubjectivity
2015/7/30
Self-consciousness is a product of evolution. Few people today disagree with the evolutionary history of humans. But the nature of self-consciousness is still to be explained, and the story of evoluti...
An introduction to the subfamily psammocharinae.
Biosynthetic introduction of aryl bromide functionality into proteins
Aryl bromide proteins bacteria e. coli phenylalanine synthetase gene plasmid bear dihydrofolate reductase
2014/12/11
Incorporation of aryl bromide functionality into proteins was achieved via engineering the bacterial biosynthetic apparatus. A phenylalanine auxotrophic E. coli host was equipped with a phenylalanyl-t...
Neural networks have seen an explosion of interest over the last few years, and are being successfully applied across an extraordinary range of problem domains, in areas as diverse as finance, medicin...
Introduction to the Asilidae Fauna (Insecta: Diptera) of Fars Province, Iran
Diptera Asilidae fauna Fars province Iran
2010/3/25
Fars province in the south of Iran was surveyed for Asilidae (Insecta: Diptera) during 2006-2007. Twenty six species, belonging to 19 genera and 7 subfamilies: Apocleinae (5 species), Asilinae (7 spec...
基因组学研究中一些常用软件的概述An Introduction of Several Programs Used in Genomic Analysis
基因组学 比对 组装 重复序列 基因
2008/1/16
摘要基因组学是以一个物种的全部遗传信息为研究对象,在整体上研究遗传信息的分子组成、组织结构、表达调控和进化等内在机制的基础性学科。基因组学研究中海量数据的存储、管理和检索,以及对这些数据进行挖掘等过程, 必须借助于生物信息学的方法。 目前,大量成熟的软件广泛地应用在基因组学研究中,它们大都可通过互联网免费访问或索取。本文拟对人类基因组计划中常用的一些软件如序列比对、序列组装、重复序列鉴定和基因预测...
利用DNA序列构建系统树的方法介绍Introduction to the Methods of ConstructingPhylogenetic Trees with DNA sequences
系统树 距离法 简约法 大似然法 贝叶斯推断法
2008/1/10
摘要
利用DNA序列进行系统发生分析是分子进化研究的必要手段。构建系统树的方法有距离法、简约法、最大似然法以及贝叶斯推断法等。要解决特定的系统发生问题,首先要挑选合理的分类群及序列,尽量减少数据的偏倚,然后选择构树方法,最后还要对结果进行评价并给出进化学上的解释。本文讨论了挑选数据的原则及存在的问题,介绍了几种构树方法的基本原理及步骤,并列举了它们的优缺点。Abstract: Construct...
基因组数据库简介Introduction to Genome Databases
微生物基因组 人类基因组 数据库系统
2007/12/31
摘要本文以北京大学生物信息中心安装的3个国际著名基因组数据库GDB、GenoList和Ensembl为基础,介绍目前常用的基因组数据库,包括这些数据数据库的内容、数据格式、使用方法,以及用于构建上述数据库的数据库管理系统。
Abstract:A brief introduction to the genome databases GDB,GenoList and Ensembl is given...