搜索结果: 1-15 共查到“知识库 leukotriene”相关记录19条 . 查询时间(0.046 秒)
Chocolate procyanidins decrease the leukotriene-prostacyclin ratio in humans and human aortic endothelial cells
Chocolate eicosanoids flavonoids
2016/6/12
Polyphenolic phytochemicals inhibit vascular and
inflammatory processes that contribute to disease. These effects
are hypothesized to result from polyphenol-mediated alterations
in cellular eicosan...
Antitussive Effects of the Leukotriene Receptor Antagonist Montelukast in Patients with Cough Variant Asthma and Atopic Cough
atopic cough cough score cough variant asthma leukotriene receptor antagonist montelukast
2010/11/12
In patients with CVA, 2-week treatment with montelukast, clenbuterol, and montelukast plus clenbuterol all significantly decreased cough scores and treatment with montelukast plus clenbuterol was supe...
Effect of Spermidine on Intracellular Calcium Ion Mobilization in Chicken Phagocytes Treated with Leukotriene B4 (LTB4)
spermidine LTB4 calcium ion chicken phagocytes
2009/7/31
The effect of spermidine, a type of polyamine present in exudates from inflamed tissues and bacteria-infected sites in humans, on calcium mobilization of leukotriene B4 (LTB4)-stimulated chicken abdom...
Dibutyryl cAMP effects on thromboxane and leukotriene production in decompression-induced lung injury
decompression neutrophil lung injury
2009/6/8
Decompression-induced venous bubble formation has been linked to increased neutrophil counts, endothelial cell injury,release of vasoactive eicosanoids, and increased vascular membrane permeability.
Leukotriene-B4 concentrations in breathing condensate before and after simulated deep dives
Biological Markers Breath Tests Chi-Square Distribution Diving
2009/6/4
During diving the respiratory tract is exposed to occupational hazards (increased oxygen partial pressure, pulmonary vessel engorgement during submersion, inert gas micro embolism during decompression...
Molecular Mechanism of the Additive Effects of Leukotriene Modifier in Asthmatic Patients Receiving Steroid Therapy
airflow limitation airway hyperresponsiveness airway lability exhaled breath condensate RANTES
2010/11/16
A significant improvement in forced expiratory volume in one second as a percentage of the predicted value (%FEV1) and Min%Max PEF was seen in the subgroup of asthma with AR. Although there was no sig...
A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis
comparative double blind study cysteinyl leukotriene receptor montelukast pranlukast seasonal allergic rhinitis
2010/11/17
Montelukast 5mg, 10mg once daily and the pranlukast 450mg/day showed significant improvements in the change from the baseline in the composite, daytime and nighttime nasal symptom scores, and the impr...
The Role of Leukotriene B4 in Allergic Diseases
allergic conjunctivitis allergic rhinitis asthma atopic dermatitis
2010/11/17
Leukotriene B4 (LTB4) is a lipid mediator with potent chemoattractant properties and that is rapidly generated from activated innate immune cells such as neutrophils, macrophages, and mast cells. Elev...
Therapeutic Effect of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, on Japanese Patients with Seasonal Allergic Rhinitis
cysteinyl leukotriene receptor dose-response relationship montelukast rhinitis allergic seasonal
2010/11/17
Background: Secretion of nasal discharge was enhanced and airway-resistance in the nasal cavity was augmented, resulting in nasal congestion, when leukotrienes were administered to the nasal mucosa. T...
Clinical Evaluation of Leukotriene Receptor Antagonists in Preventing Common Cold-like Symptoms in Bronchial Asthma Patients
acute exacerbation asthma common cold-like symptoms ICS LTRAs
2010/11/18
Adult asthma patients undergoing treatment with LTRAs exhibit lower incidence rates of common cold-like symptoms than those not receiving LTRAs. LTRAs play an important role in reducing the incidence ...
Effects of KP-496, a Novel Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors, on Contractions Induced by Various Agonists in the Guinea Pig Trachea
antagonist anti-asthmatic drugs asthma leukotriene D4 thromboxane A2
2010/11/19
KP-496 produced parallel rightward shifts of the LTD4 and U46619 concentration-response curves in a concentration-dependent manner. Schild plot analyses of the antagonistic activities of KP-496 demons...
Population-based open-label clinical effectiveness assessment of the cysteinyl leukotriene receptor antagonist pranlukast
asthma pranlukast questionnaire symptom treatment
2010/11/26
Although the efficacy of cysteinyl leukotriene receptor antagonists in asthma therapy has been established through controlled clinical trials, there are no data concerning the effectiveness of their u...
Effect of a leukotriene receptor antagonist, pranlukast hydrate, on airway inflammation and airway hyperresponsiveness in patients with moderate to severe asthma
airway hyperresponsiveness airway inflammation asthma eosinophils leukotriene leukotriene receptor antagonist
2010/11/25
Asthma is characterized by chronic airway inflammation and the recruitment of inflammatory cells, typically eosinophils and lymphocytes, into the airway. Although several chemical mediators are releas...
Inhibitory effect of olopatadine hydrochloride (KW-4679), a novel antiallergic drug, on peptide leukotriene release from human eosinophils
antiallergic drug human eosinophils leukotriene olopatadine
2010/11/25
Olopatadine hydrochloride (olopatadine; KW-4679), (Z)-11-[(3-dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid monohydrochloride, is an antiallergic drug with selective and potent...
Additive effect of cysteinyl leukotriene or thromboxane modifiers to inhaled corticosteroids in asthmatic patients
asthma corticosteroid cysteinyl leukotriene thromboxane
2010/11/22
Bronchial asthma is a chronic inflammatory disease of the conducting airways. Current asthma treatment guidelines recommend inhaled corticosteroids (ICS) as the first-line maintenance therapy for mild...