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2020年8月6日，上海交通大学医学院/上海市免疫学研究所梁启明课题组联合美国南加州大学医学院赵振课题组在Cell Stem Cell杂志在线发表了题为The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis的文章。该研究表明，寨卡病毒C蛋白（Capsid pro...
Stem cells are defined by capacities for both self-renewal and differentiation. Many different entities satisfy this working definition. Explicating the stem cell concept reveals it to be relational a...
Isolation and In vitro Culture of Pig Spermatogonial Stem Cell
Spermatogonial Stem Cell SSC Pluripotency Long Term Culture Pig
2016/4/29
The present study identified the favorable conditions for isolation, enrichment and in vitro culture of highly purified, undifferentiated pig spermatogonial stem cell (SSC) lines that proliferate for ...
Obstacles and Circumvention Strategies for Hematopoietic Stem Cell Transduction by Recombinant Adeno-associated Virus Vectors
gene therapy hematopoietic stem cells sickle cell disease
2015/5/21
High-efficiency transduction of hematopoietic stem cells (HSCs) by recombinant adeno-associated virus serotype 2 (AAV2) vectors is limited by (i) inadequate expression of cellular receptor/co-receptor...
Adipose stem cell combined with plasma-based implant bone tissue differentiation in vitro and in a horse with a phalanx digitalis distalis fracture: a case report
hoof bone fracture fat tissue plasma implant in vitro differentiation horse
2015/4/15
A horse suffering from an undetected hoof bone fracture was diagnosed three weeks after injury. The formation of callus tissue was detected at the fracture site. Standard orthopaedic screw application...
Augmentation of bone healing of nonunion fracture using stem cell based tissue engineering in a dog: a case report
adipose derived stem cells scaffold nonunion fracture
2015/4/2
A 4-year-old, intact male crossbreed dog, weighing 27 kg, was referred for the treatment of a nonunion fracture. The radiographs revealed displacement of the radius and ulna bone fracture fragment and...
Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization
Rac Cdc42
2014/12/12
Critical to homeostasis of blood cell production by hematopoietic stem/progenitor (HSC/P) cells is the regulation of HSC/P retention within the bone marrow microenvironment and migration between the b...
Effects of Capsaicin on Adipogenic Differentiation in Bovine Bone Marrow Mesenchymal Stem Cell
Bovine Bone Marrow Mesenchymal Stem Cells [BMSCs] Capsaicin Adipogenesis Differentiation Apoptosis
2016/5/17
Capsaicin is a major constituent of hot chili peppers that influences lipid metabolism in animals. In this study, we explored the effects of capsaicin on adipogenic differentiation of bovine bone marr...
Twenty Years of Experience on Stem Cell Transplantation in Iran
Hematopoietic Stem Cell Transplantation Leukemia Beta-Thalassemia
2015/9/29
Background: Hematopoietic stem cell transplantation (HSCT) is a new window to therapy of many diseases. From March 1991 through April 2011, a total of 3237 HSCT were performed in the Hematology-Oncolo...
Engineering of the Embryonic and Adult Stem Cell Niches
Stem Cells Biocompatible Materials Cellular Microenvironment Cell Differentiation
2015/9/29
Context: Stem cells have the potential to generate a renewable source of cells for regenerative medicine due to their ability to self-renew and differentiate to various functional cell types of the ad...
Inhibition of the Renin Angiotensin System during Autologous Stem Cell Transplant Does Not Impact Time to Engraftment
Multiple Myeloma ACE Inhibitor Angiotensin Receptor Blocker Melphalan Neutropenia
2013/1/30
Background: The renin angiotensin system RAS modulates hematopoiesis via local effects in the bone marrow. Angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) may ...
Related cord blood banking for haematopoietic stem cell transplantation
related cord blood banking related donor cord blood programme stem cell transplantation
2011/9/26
The aims of this single centre study were to assess the feasibility of related cord blood collecting, the appropriateness of storage and the final suitability for transplantation. Since September 1994...
SIRT1 DEFICIENCY COMPROMISES MOUSE EMBRYONIC STEM CELL DIFFERENTIATION, AND EMBRYONIC AND ADULT HEMATOPOIESIS IN THE MOUSE
Mouse Embryonic Stem Cell Hematopoietic Cell Differentiation
2015/5/21
SIRT1 (Sirtuin 1) is a founding member of a family of seven proteins and histone deacetylases. It is involved in cellular resistance to stress, metabolism, differentiation, aging, and tumor suppressio...
Bayesian inference and model choice in a hidden stochastic two-compartment model of hematopoietic stem cell fate decisions
Stochastic two-compartment model hidden Markov models reversible jump MCMC hematopoiesis stem cell asymmetric division
2010/11/8
Despite rapid advances in experimental cell biology, the in vivo behavior of hematopoietic stem cells (HSC) cannot be directly ob-served and measured. Previously we modeled feline hematopoiesis using ...
Experimental Standards: evaluating success in stem cell biology
experiment stem cells epistemic history
2011/9/5
This paper aims to bring the epistemic dimensions of stem cell experiments out of the background, and show that they can be critically evaluated. After introducing some basic concepts of stem cell bio...