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Effects of dietary sodium on metabolites: the Dietary Approaches to Stop Hypertension (DASH)–Sodium Feeding Study
metabolomics epidemiology sodium intake trial high and low sodium intake feeding trial African American
2018/11/20
Background: High sodium intake is known to increase blood pressure and is difficult to measure in epidemiologic studies.
Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y
airway inflammation, metabolomics, polyunsaturated fatty acids, prenatal programming, vitamin D
2018/11/16
Background: Vitamin D deficiency is implicated in a range of common complex diseases that may be prevented by gestational vitamin D repletion. Understanding the metabolic mechanisms related to in uter...
Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y
airway inflammation metabolomics polyunsaturated fatty acids prenatal programming vitamin D
2018/11/20
Background: Vitamin D deficiency is implicated in a range of common complex diseases that may be prevented by gestational vitamin D repletion. Understanding the metabolic mechanisms related to in uter...
Association of TCN2 rs1801198 c.776G>C polymorphism with markers of one-carbon metabolism and related diseases: a systematic review and meta-analysis of genetic association studies
cobalamin c.776G>C genetic association studies
2018/11/20
Background: Vitamin B-12 (cobalamin) deficiency may produce severe neurologic and hematologic manifestations. Approximately 20–25% of circulating cobalamin binds to transcobalamin 2 (TCN2), which is r...
Modeling the dose effects of soybean oil in salad dressing on carotenoid and fat-soluble vitamin bioavailability in salad vegetables
bioavailability, carotenoid, concordance, lipid, triglyceride, vitamin A, vitamin E, vitamin K
2018/11/20
Background: Previously, we showed that vegetable oil is necessary for carotenoid absorption from salad vegetables. Research is needed to better define the dose effect and its interindividual variation...
Testing the direction of effects between child body composition and restrictive feeding practices: results from a population-based cohort
feeding feeding behavior parenting restriction childhood obesity BMI body composition longitudinal studies children general population
2018/11/16
Background: Parental restrictive feeding (i.e., limiting food intake of children) has been linked to childhood overweight. However, the directionality of the causal pathway remains unknown.
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial
isoflavone bone turnover bioavailability probiotics osteopenia postmenopause equol bone density
2018/11/19
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therap...
The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure
intestinal absorption intestinal malabsorption intestinal
2018/11/19
Background: In research settings that use metabolic balance studies (MBSs) of stable adult patients with short bowel syndrome, intestinal failure (IF) and dependence on parenteral support (PS) have be...
The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure
intestinal absorption intestinal malabsorption intestinal
2018/11/16
Background: In research settings that use metabolic balance studies (MBSs) of stable adult patients with short bowel syndrome, intestinal failure (IF) and dependence on parenteral support (PS) have be...
Vitamin D and dementia risk: the cause and consequence story
vitamin D dementia disentangle Indeed
2018/11/16
We read with great interest the article by Olsson et al. (1), which examined the association of vitamin D with dementia risk in a cohort of Swedish men. This study measured plasma 25-hydroxyvitamin D ...
Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes
trimethylamine-N-oxide type 2 diabetes flavin monooxygenase 3 polymorphisms nutrition metabolite
2018/11/19
Background: The association of trimethylamine-N-oxide (TMAO), a microbiota-dependent metabolite from dietary choline and carnitine, with type 2 diabetes was inconsistent.
Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes
trimethylamine-N-oxide type 2 diabetes flavin monooxygenase 3 polymorphisms, nutrition metabolite
2018/11/16
Background: The association of trimethylamine-N-oxide (TMAO), a microbiota-dependent metabolite from dietary choline and carnitine, with type 2 diabetes was inconsistent.
Maternal protein intake in pregnancy and offspring metabolic health at age 9–16 y: results from a Danish cohort of gestational diabetes mellitus pregnancies and controls
pregnancy gestational diabetes mellitus protein insulin body composition
2018/11/15
Background: Recent years have seen strong tendencies toward high-protein diets. However, the implications of higher protein intake, especially during developmentally sensitive periods, are poorly unde...
Nutritional metabolomics and breast cancer risk in a prospective study
breast cancer diet nutrition metabolomics biomarker tocopherol alcohol androgen fat
2018/11/15
Background: The epidemiologic evidence for associations between dietary factors and breast cancer is weak and etiologic mechanisms are often unclear. Exploring the role of dietary biomarkers with meta...
Metabolism of uniformly labeled 13C-eicosapentaenoic acid and 13C-arachidonic acid in young and old men
aging arachidonic acid docosahexaenoic acid eicosapentaenoic acid metabolism
2018/11/15
Background: Plasma eicosapentaenoic acid (EPA) and arachidonic acid (AA) concentrations increase with age.