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Dissecting the expression landscape of RNA-binding proteins in human cancers
RNA-binding proteins cancer pathogenesis
2015/3/5
Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by controlling gene expression at the post-transcriptional level. Results We explore the expression of more than 800...
Dispersal of Golgi matrix proteins during mitotic Golgi disassembly
Golgi apparatus Biogenesis Golgin GRASP
2009/12/23
During mitosis, the mammalian Golgi disassembles into
numerous vesicles and larger membrane structures
referred to as clusters or remnants. Following mitosis, the
vesicles and clusters reassemble t...
Location proteomics - Building subcellular location trees from high resolution 3D fluorescence microscope images of randomly-tagged proteins
Location proteomics 3D fluorescence microscope images
2009/12/23
The overall object of proteomics is to characterize all of the proteins expressed in a given cell type. With the rapiddevelopment of random gene tagging technology and high resolution fluorescence mic...
Research, part funded by the Medical Research Council, has found that a crafty family of ‘limpet-like’ proteins can play a crucial role in repairing DNA damage – according to two research papers publi...