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Involvement of the testes - one of the most common sites of relapse in Acute Lymphoblastic Leukemia (ALL) - usually presents with painless enlargement of one or both testes. Testicular involvement occ...
Immunoglobulin heavy chain rearrangements provide a specific identity of complementarity determining region 3 (CDR3) DNA sequences. For this reason, CDR3 regions may be used in the diagnosis of malign...
Hepatomegaly and mild elevation of serum transaminase values that might be caused by infiltration of leukemic cells are seen in some cases of leukemia. It may result from such conditions as viral hep...

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