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Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad
autocrine signaling bone marrow cells breast cancer
2014/11/6
Breast cancer metastasis to bone triggers a vicious cycle of tumor growth linked to osteolysis. Breast cancer cells and osteoblasts express the epidermal growth factor receptor (EGFR) and produce ErbB...
Soft-diet Feeding Inhibits Adult Neurogenesis in Hippocampus of Mice
Mastication Neurogenesis Neurotrophin
2010/1/21
Our previous study showed that mice fed on a soft diet after weaning had reduced levels of brain-derived neurotrophic factor (BDNF) protein in the hippocampus after 3 months of age compared with mice ...
An M-CSF Receptor c-Fms Antibody Inhibits Mechanical Stress–Induced Root Resorption during Orthodontic Tooth Movement in Mice
c-Fms Odontoclast Root resorption Mouse Orthodontics
2010/3/5
Objective: To examine the effect of anti-c-Fms antibody on odontoclastogenesis and root resorption in an orthodontic tooth movement mouse model.
Materials and Methods: We used orthodontic tooth mov...
Soft-diet Feeding Inhibits Adult Neurogenesis in Hippocampus of Mice
Mastication Neurogenesis Neurotrophin
2010/12/1
Our previous study showed that mice fed on a soft diet after weaning had reduced levels of brain-derived neurotrophic factor (BDNF) protein in the hippocampus after 3 months of age compared with mice ...