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Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion. But researchers from the Univers...
Background:: CCR5 is a receptor for CCL3 (MIP-1 α), CCL4 (MIP-1 α) and CCL5 (regulated on activation normal T cell expressed and secreted (RANTES)) and play important roles in recruitment of NK cells ...
University of Queensland researchers have made a major leap forward in treating renal disease, today announcing they have grown a kidney using stem cells.
Mesenchymal stem cells (MSCs) are characterized by ability to differentiate into several cell types and self-renewability. These stem cells have a limited capacity in cell lineage differentiation incl...
中国医学科学院实验血液学国家重点实验室韩忠朝课题组在Cell Transplant期刊上发表"Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis."
中国医学科学院实验血液学国家重点实验室王建祥课题组在在Leukemia期刊发表文章"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.”
Background: Th17-inducing activity is carried by certain polysaccharides such as β-glucan derived from Candia albicans. Our previous studies have shown that Th1- and Th2-inducing activities can be qua...
Th1 cells, which express IL-18R, produce IFN-γ in response to Ag and IL-2 and increase further production of IFN-γ upon additional IL-18 stimulation. They simultaneously produce Th2 cytokines (IL-9 an...
Background: Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes. In this study, we investigated the effect of n...
Aim: It is generally accepted that proinflammatory cytokines secreted by mononuclear cells are responsible for pancreatic beta (B) cell destruction in animal models of autoimmune type-1 diabetes melli...
α-GalCer treatment significantly suppressed EC in the thymus-intact mice that had not been treated with anti-CD25 Ab. In contrast, α-GalCer treatment of thymectomized and anti-CD25 Ab-treated mice did...
The G-protein-coupled receptors (GPCRs) are the largest known group of integral membrane receptor proteins and are the most common targets of pharmacotherapy. Mast cells (MCs) have been reported to pl...
Multiple sclerosis (MS) is a CD4+ T cell-mediated autoimmune disease affecting the central nervous system. It was largely accepted that Th1 cells driven by IL-12 were pathogenic T cells in human MS an...
Rheumatoid arthritis is a chronic disease that affects multiple joints. It is considered to be an autoimmune disease in which a T helper (Th)-1 type response has been implicated to play an important p...
专著信息 书名 Comparison of Bone Marrow Mobilization with Bone Marrow-Derived Mononuclear Cells Transplantation for the Therapy of Myocardial Infarction in Rabbits. 语种 英文 撰写或编译 作者 刘宏伟,盖鲁粤 第一作者单位 出版社 Circula...

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