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Role of the Dorsomedial Hypothalamus in Responses Evoked from the Preoptic Area and by Systemic Administration of Interleukin-1β
dorsomedial hypothalamus preoptic area hypothalamus paraventricular nucleus Fos body temperature heart rate ACTH
2015/5/21
Recent studies in anesthetized rats suggest that autonomic effects relating to thermoregulation that are evoked from the preoptic area (POA) may be mediated through activation of neurons in the dorsom...
Aerobic Training Activates Interleukin 10 for Colon Anticarcinogenic Effects
COLON CANCER PRENEOPLASTIC LESIONS INFLAMMATION PHYSICAL TRAINING
2017/4/20
Purpose: Physical exercise has been shown to be protective against colon carcinogenesis. Physical exercise, however, covers a wide range of modalities, from which different effects on the human body h...
Interleukin-2 Expression in Lupoid and Usual Types of Old World Cutaneous Leishmaniasis
Leishmaniasis Interleukin-2 Granulomatous
2015/10/15
Background: Interleukin (IL)-2 plays a central role in T cell-dependent immune responses.
An increasing body of evidence implicates proinflammatory cytokines in psychiatric disorders, namely, in depression. Of notice, recent studies showed that anti-inflammatory cytokines, such as IL-10, a...
Spontaneous production of interleukin-5 and its heterogeneous effect on eosinophils in an adult T-cell leukemia patient
adult T-cell leukemia eosinophil heterogeneity interleukin-5
2010/11/25
We examined the functional heterogeneity of eosinophils from an adult T-cell leukemia (ATL) patient with eosinophilia. A 63-year-old man was admitted to our hospital because of lymphadenopathy. The le...
Interleukin-4 is involved in allergen-induced airway eosinophilic inflammation and bronchial hyperresponsiveness independent of genetic background
bronchial hyperresponsiveness eosinophils IgE interleukin-4 mice
2010/11/26
The role of interleukin (IL)-4 in the development of allergen-induced airway inflammation and bronchial hyperresponsiveness (BHR) is still controversial. To investigate the role of IL-4 in the develop...
Interleukin-10 inhibits the production of inflammatory cytokines by antigen-stimulated mononuclear cells from asthmatic patients
bronchial asthma granulocytemacrophage colony stimulating factor interferon-γ interleukin-1β interleukin-2 interleukin-5 interleukin-10
2010/11/25
Bronchial asthma, characterized by chronic airway inflammation, involves many inflammatory cytokines. Interleukin (IL)-10 is a potent inhibitor of cytokine synthesis. Thus, the effects of IL-10 were e...
Low-dose exogenous interleukin (IL)-12 enhances antigen-induced interferon-γ production without affecting IL-10 production in asthmatics
bronchial asthma Dermatophagoides farinae interferon-γ interleukin-10 interleukin-12 peripheral blood mononuclear cells
2010/11/25
The production of IFN-γ by PBMC was significantly enhanced by incubation with IL-12 in both patient groups (P < 0.05), while IL-12 did not affect the production of IL-10 in either group. Lymphocyte pr...
Interleukin-18 is associated with the severity of atopic dermatitis
atopic dermatitis bronchial asthma IgE interferon-γ interleukin-18 interleukin-18 promoter
2010/11/24
The plasma IL-18 level was elevated, particularly in patients with atopic dermatitis. As the clinical severity of atopic dermatitis increased, the plasma IL-18 level also tended to increase. These fin...
Reduced Serum Antibody Production and Acute Airway Inflammation in Interleukin 6-deficient Mice Challenged with Ovalbumin
animal asthma cytokine eosinophil IL-6
2010/11/19
Background: IL-6 is a unique cytokine that has pro- and anti-inflammatory property. The purpose of this study was to clarify the role of IL-6 in the allergic airway inflammation.
Methods: We challeng...
The Role of Interleukin-9 in Asthma
airway hyperresponsiveness asthma interleukin-9 interleukin-9 receptor mucus overproduction
2010/11/19
Interleukin (IL)-9 is a pleiotropic Th2 type cytokine which has been shown to play an important role in the pathogenesis of bronchial asthma. This review will concentrate on the structure, the source,...
Recurrent Non-Typhoidal Salmonella Bacteremia in a Patient with Interleukin -12p40 Deficiency
Immunologic Deficiency Syndromes Interleukin-12 Iran
2010/2/8
The South eastern region of Iran is an endemic area for salmonellosis. Sometimes bacteremia due to nontyphoidal salmonella occurs but certain patients are at increased risk for recurrent bacteremia. T...