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Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate
bisphosphonates alendronate animal models
2014/12/4
Summary One year of high-dose bisphosphonate (BPs) therapy in dogs allowed the increased accumulation of advanced glycation end-products (AGEs) and reduced postyield work-to-fracture of the cortical b...
Theoretical analysis of alendronate and risedronate effects on canine vertebral remodeling and microdamage
bisphosphonate bone remodeling
2014/12/4
Bisphosphonates suppress bone remodeling activity, increase bone volume, and significantly reduce fracture risk in individuals with osteoporosis and other metabolic bone diseases. The objectives of th...