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Expression of Glucose Transporter 4 (GLUT4) is Increased by Cinnamaldehyde in C2C12 Mouse Muscle Cells
Glucose Transporter type 4 Cinnamaldehyde Real-Time Polymerase Chain Reaction Diabetes Mellitus Insulin
2015/10/10
Background:: In diabetes mellitus because of the absence or insufficient sensitivity to insulin, glucose transporter protein in cell membrane, glucose transporter 4, is decreased. GLUT4 is the major g...
Tissue Engineering Using Human Mineralized Bone Xenograft and Bone Marrow Mesenchymal Stem Cells Allograft in Healing of Tibial Fracture of Experimental Rabbit Model
Bone Xenograft Allograft Mesenchymal stem cells Healing Rabbit
2015/9/25
Background: Bone healing and its reconstruction in fractures, especially in long bones are of particular importance in regenerative medicine. This study compares the bone healing rate after a human xe...
Pattern secretion of matrix Metalloproteinases and their biological tissue inhibitors by human glomerular mesangial cells in culture
Metalloproteinases Mesangial cell Glomerulosclerosis
2010/1/5
The glomerular mesangial cells (GMC) play a central role in the synthesis and turnover of the glomerular mesangial matrix. The breakdown of the matrix likely depends on the balance between of a variet...
Protective effects of antioxidants on high Glucose-induced malfunctions in human glomerular mesangial cells
Mesangial cells High glucose extracellular matrix
2009/12/31
Altered functions of mesangial cells induced by high glucose concentrations are thought to play an important role in the pathogenesis of diabetic nephropathy. We therefore investigated the effect of h...
The 14kDa Protein Molecule Isolated from Garlic Suppresses Indoleamine 2, 3-Dioxygenase Metabolites in Mononuclear Cells In vitro
Garlic Indoleamine 3-dioxygenase Proliferation Tryptophan
2009/12/11
A wide range of biological activities of garlic in vitro and in vivo have been verified including its antioxidant, antitumor and anti-inflammatory effects. Indoleamine 2,3-dioxygenase (IDO) is an enzy...
The 14kDa Protein Molecule Isolated from Garlic Suppresses Indoleamine 2, 3-Dioxygenase Metabolites in Mononuclear Cells In vitro
Garlic Indoleamine 3-dioxygenase Proliferation Tryptophan
2009/12/11
A wide range of biological activities of garlic in vitro and in vivo have been verified including its antioxidant, antitumor and anti-inflammatory effects. Indoleamine 2,3-dioxygenase (IDO) is an enzy...
厦门大学医学院研究论文发表在Stem Cells杂志
厦门大学医学院 Stem Cells
2009/7/27
干细胞研究近年来一直是生命科学研究的热点之一。角膜上皮干细胞是维持角膜上皮动态稳定以及上皮损伤修复的细胞来源。角膜上皮干细胞的研究对于严重眼表面疾病的治疗以及角膜组织工程研究具有重要意义。但是，由于干细胞缺乏特异性的表面标记物，影响了干细胞研究的进一步深入。近日，医学院眼科研究所刘祖国教授课题组的一项研究发现，核浆双向转运受体蛋白 Importin 13 可以作为角膜上皮干细胞的一个标志物...
Dendritic Cells—Importance in Allergy—
asthma atopic dermatitis contact dermatitis Th1/Th2
2010/11/18
In this review we discuss the role of dendritic cells (DC) in the pathogenesis of allergic contact hypersensitivity (ACH) and atopic disorders, such as asthma and atopic eczema. In ACH patients, DC re...
Overexpression of Protein Tyrosine Phosphatase 1B in HepG2 Cells Ameliorates Insulin-mediated Suppression of Apolipoprotein B mRNA Translation Via Its Untranslated Regions
Protein tyrosine phosphatase 1B Untranslated region In vitro translation assay
2010/4/19
Background: The hepatic secretion of apolipoprotein B (apoB), containing lipoproteins, is known to be regulated by insulin, and the overproduction of these atherogenic lipoproteins occurs in insulin-r...
BIOSORPTION OF CR (VI) BY RESTING CELLS OF ASPERGILLUS SP.
Aspergillus sp. batch biosorption chromium (VI) Langmuir adsorption isotherm resting cells
2010/4/6
Biosorption of Cr(VI) from aqueous solution was studied in a batch bioreactor using the resting cells of filamentous fungal biomass (Aspergillus sp.) isolated from industrial wastewaters. The specific...
Dendritic Cells Bearing HLA-G Inhibit T-Cell Activation in Type 1 Diabetes
Dendritic cell HLA-G IFN-β (Interferon β)
2010/4/2
HLA-G is normally expressed on human trophoblast cells. It is a non-classical MHC molecule class I b. The role of HLA-G in diabetic type 1 is not known.We investigated the role of IFN-β in induction H...
COMPARISON OF LIPOAMIDE DEHYDROGENASE ACTIVITY IN HL-60 LEUKEMIA CELLS AND NORMAL LYMPHOCYTE
Lipoamide dehydrogenase Lymphocyte HL-60
2010/4/19
To determine the importance of Q10H2 as an antioxidant in cancer, we measured the activity of lipoamide dehydrogenase (Q10H2 recycling enzyme) in HL-60 and normal lymphocyte. The cultured cells of HL-...
Production of Matrix Metalloproteinases in Human Cultured Mast Cells: Involvement of Protein Kinase C—Mitogen Activated Protein Kinase Kinase—Extracellular Signal-regulated Kinase Pathway
human cultured mast cells matrix metalloproteinase-9 membrane type matrix metalloproteinase tissue inhibitor of metalloproteinase-1 tissue inhibitor of metalloproteinase-2
2010/11/18
We detected the de novo synthesis of MMP-9 in HCMC after stimulation with PMA and found that the synthesis was mediated through protein kinase C—mitogen activated protein kinase kinase (MEK)—ERK pathw...
Inhalant corticosteroids inhibit mechanical strain-induced RANTES and eotaxin production by human airway smooth muscle cells
airway smooth muscle cells eotaxin inhaled corticosteroids mechanical strain RANTES
2010/11/24
The results showed that: (i) mechanical strain, including stretch and compression, stimulated ASM cells to produce RANTES and eotaxin; and (ii) FP and BUD inhibited mechanical strain-induced and TNF-α...
Positional Effect of Amino Acid Replacement on Peptide Antigens for the Increased IFN-γ Production from CD4T Cells
analogue peptide complementarity determining region 3 interferon gamma peptide antigens T-cell antigen receptor
2010/11/19
Background: Based on the fact that site-specific amino acid replacement on peptide antigens stimulated T cell clones to produce increased amount of IFN-γ, we investigated this structure-function relat...