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Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies
25-hydroxyvitamin D cardiovascular disease meta-analysis dose-response CVD mortality
2018/11/13
Background: During the past decade, an increasing number of prospective studies have focused on the association between vitamin D and cardiovascular disease (CVD). However, the evidence on the relatio...
A dose-response crossover iodine balance study to determine iodine requirements in early infancy
iodine infants iodine requirement iodine balance iodine intake iodine deficiency
2018/12/13
Background: Optimal iodine intake during infancy is critical for brain development, but no estimated average requirement (EAR) is available for this age group.
Heart rate variability and fatty acid content of blood cell membranes: a dose-response study with n−3 fatty acids
sudden cardiac death cardiac arrest ventricular arrhythmias
2016/6/1
Dietary intake of long-chain n23 polyunsaturated
fatty acids (PUFA) may protect against sudden cardiac
death, an event that may be predicted by measurement of heart
rate variability (HRV).
Acute effects of quercetin-3-O-glucoside on endothelial function and blood pressure: a randomized dose-response study
blood pressure cardiovascular disease endothelial function nitric oxide quercetin
2018/12/3
Background: Epidemiologic studies have suggested that a flavonoid-rich diet can reduce the risk of developing cardiovascular disease. Certain flavonoids, in particular quercetin, have been shown to am...
Low-Active Male Adolescents: A Dose Response to High-Intensity Interval Training
YOUTH HEALTH PHYSICAL ACTIVITY FITNESS
2017/4/13
Purpose: High-intensity interval training (HIIT) is a potential alternative to traditionally recommended steady state exercise for providing health benefits in adolescents, yet its dose–response relat...
Association between alcohol consumption and the risk of incident type 2 diabetes: a systematic review and dose-response meta-analysis
alcohol meta-analysis type 2 diabetes systematic review dose-response
2018/11/28
Background: Previous cohort studies have shown that moderate alcohol consumption was associated with a lower risk of type 2 diabetes (T2D). However, whether these associations differ according to the ...
Curvilinear Dose–Response Relationship of Carbohydrate (0–120 g·h−1) and Performance
CYCLING TIME TRIAL CARBOHYDRATE INGESTION RATE
2017/7/14
Background: There is a lack of consensus regarding the optimal range of carbohydrate (CHO) ingestion rates recommended for endurance athletes.
Purpose: This study investigated the relationship betwee...
Oxygen as a drug: A dose response curve for radiation necrosis
Hyperbaric Oxygenation Radiation necrosis oxygen dose animal rabbit macrophage Oryctologus cunicul
2009/5/26
This paper was first presented at the Undersea
and Hyperbaric Medical Society’s 1993 Annual Scientific
Meeting. It was accepted for the SPUMS Annual
Scientific Meeting 1994 because the audience was...
Dose-response studies on male reproductive parameters in dogs with nafarelin acetate, a potent LHRH agonist
LHRH agonist nafarelin acetate EDNal(2)6JLHRH spermatogenesis prostate male dogs
2009/2/20
Adult male beagle dogs were administered daily subcutaneous injections of either 0.5 or 2.0 micrograms/kg of a potent LHRH agonist, nafarelin acetate, for 44 days. Although there was a rise in the c...
Dose-response effects of gonadotropin-releasing hormone on plasma concentrations of gonadotropins and testosterone in fertile and subfertile stallions
gonadotropin-releasing hormone luteinizing hormone follicle-stimulating hormone testosterone horse fertility
2009/2/11
Five fertile and five subfertile stallions were treated with a single intravenous injection of saline the first week followed by a single intravenous injection of varying doses of gonadotropin-rel...
Dose–Response Relationship Between Testosterone and Erectile Function: Evidence for the Existence of a Critical Threshold
Androgens erection neural NOS phosphodiesterase type 5 prostate
2008/12/24
Androgens play an important role in erectile function. However, the dose–response relationship between plasma testosterone levels and penile erection remains unclear. Intact (sham operated) or bi...
Permanent Induction of Morphological Abnormalities in the Penis and Penile Skeletal Muscles in Adult Rats Treated Neonatally With Diethylstilbestrol or Estradiol Valerate：A Dose-Response Study
Estrogen DES fertility testosterone bulbocavernosus
2008/12/22
This study evaluated the effects of neonatal exposure to different doses of diethylstilbestrol (DES) or estradiol valerate (EV) on penile morphology, penile skeletal muscles, and fertility. Male pup...
The capacity of short-chain fructo-oligosaccharides to stimulate faecal bifidobacteria: a dose-response relationship study in healthy humans
healthy fructo-oligosaccharides
2008/4/23
Short-chain fructo-oligosaccharides (scFOS) are well-known for their bifidogenicity. In a large study comprising 200 healthy volunteers, we determined the bifidogenic properties of 7 non-digestible ca...
Dose-response relationship for inhaled corticosteroids and the add-on effect of long-acting β2-adrenergic receptor agonists in adult chronic asthmatics
add-on effect bronchial asthma dose-response relationship inhaled corticosteroids long-acting β2adrenergic receptor agonist
2010/11/22
Therapy with inhaled corticosteroids (ICS) has been regarded as first-line treatment for persistent asthma because of its highly potent anti-inflammatory effects. However, the limitations of such ther...
Teaching Pharmacodynamics: An Introductory Module On Learning Dose-Response Relationships
Pharmacodynamics dose-response drug-receptor interaction Socratic teaching pharmacology
2018/3/26
The introductory pharmacodynamics course entitled, Principles of Pharmacology, was designed as an active-learning exercise to help students discover basic pharmacology principles associated with dose-...