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Identification of androgen binding-protein（ABP）from testis and epididymis of the seasonal rodent, Octodon degus（Molina, 1872）
androgen binding-protein (ABP) testis seasonal rodent Octodon degus (Molina, 1872)
2009/2/23
ABP, a Sertoli cell secretory product, was identified in the seasonal rodent Octodon degus (Molina, 1872). It was shown to be present in cytosols from the testis and epididymis. It migrated with a...
Effect of germ cells on vectorial secretion of androgen binding protein and transferrin by immature rat Sertoli cells in vitro
germ cells vectorial secretion androgen binding protein transferrin immature rat Sertoli cells
2009/2/23
The influence of germ cells (greater than 85% pachytene spermatocytes) on vectorial secretion of androgen binding protein (ABP) and transferrin by immature rat Sertoli cells was investigated using t...
The heterogeneity of rat androgen binding protein（rABP）in the vascular compartment differs from that in the testicular tubular lumen. Further evidence for bidirectional secretion of rABP
rat ABP ABP heterogeneity
2009/2/23
Fractionation of testicular extracts and serum on a Concanavalin A-Sepharose column resolved two peaks of immunoreactive rat androgen binding protein. The rat androgen binding protein in the first pea...
Concentrations of free testosterone, total testosterone, and androgen binding protein in the peripheral serum of male rats during sexual maturation
free testosterone total testosterone androgen binding protein peripheral serum male rats
2009/2/23
To investigate the relationship between free testosterone and sexual maturation in the male rat, animals were decapitated every 5 days from 25 through 75 days of life. Serum was assayed for androgen...
The effects of the indazole carboxylic acid derivative, tolnidamine, on testicular function：I. Early changes in androgen binding protein secretion in the rat
tolnidamine rABP LH FSH testosterone
2009/2/20
The indazole carboxylic acid derivative, tolnidamine, has marked antispermatogenic activity in several animal species. In this study, we assessed the effect of tolnidamine on rat Sertoli cell functi...
Secretion of androgen binding protein by Sertoli cells is influenced by contact with germ cells
androgen binding protein Sertoli cells germ cells
2009/2/20
Sertoli cells were cultured alone or with germ cells to evaluate the effect of the association with germ cells on the secretory activity of Sertoli cells. Secretion of androgen-binding protein, whic...
Competition of the Histamine H2 Antagonist Cimetidine for Androgen Binding Sites in Man
cimetidine androgen binding prostate testis
2009/2/18
Gynecomastia and impotence have been described as side-effects of cimetidine therapy. It has previously been shown that cimetidine possesses antiandrogenic properties and competes for dihydrotesto...
Multiple Forms of Rat Testicular Androgen Binding Protein：Physicochemical Properties and the Effect of Ca++
testis androgen binding protein calcium rat ABP
2009/2/18
The presence of two forms of androgen binding protein (ABP) was confirmed in rat testicular cytosol. Each was distinctly separated from the other by DEAE-cellulose chromatography and showed a sing...
Androgen binding protein secretion and endocytosis by principal cells in the adult rat epididymis and during postnatal development
Androgen binding protein secretion endocytosis principal cells adult rat epididymis
2009/2/18
Androgen binding protein (ABP) has been shown to be secreted by Sertoli cells and to be actively taken up by the efferent ducts and proximal caput epididymidis and, yet, to be present at high concen...
Analysis of promoter and androgen regulatory sequences required for optimal transcription of the rat androgen-binding protein gene
Androgen-binding protein (ABP) sex hormone-binding globulin (SHBG) Sertoli cells transcriptional regulation
2009/2/17
The androgen-binding protein (ABP) gene P1 promoter directs cell-specific gene regulation of ABP secreted by Sertoli cells. A recent study using the mouse Sertoli cell line (MSC-1) with a luciferase...
Secreted products and extracellular matrix from testicular peritubular myoid cells influence androgen-binding protein secretion by Sertoli cells in culture
Cocultures parabiotic cultures dibutyryl cyclic AMP Sertoli cells peritubular myoid cells
2009/2/13
Metabolic cooperation mediated by secreted factors between Sertoli cells and peritubular myoid cells has been well documented. We have confirmed that factors secreted by peritubular myoid cells mo...
GnRH-A induced arrest of spermiogenesis in rats is associated with altered androgen binding protein distribution in the testis and epididymis
GnRH-antagonist Sertoli cell spermatogenesis
2009/2/10
This study examines the effects of a potent gonadotropin releasing hormone (GnRH)-antagonist (GnRH-A, Ac-D[2] Nal1, 4-CL-D Phe2, D-Trp3, D-Arg6, D-Ala10) upon the distribution of androgen binding pr...
Endocytosis of androgen-binding protein, clusterin, and transferrin in the efferent ducts and epididymis of the ram
Testicular proteins uptake excurrent ducts
2009/2/7
The amount of androgen-binding protein (ABP) in luminal fluid from the central caput epididymidis of the ram, on a per sperm basis, remains the same as that in rete testis fluid (RTF) entering the...
Androgen-Binding Protein and Reproduction: Where Do We Stand?
Androgen-Binding Protein Reproduction
2008/12/8
Androgen-binding protein (ABP) is a testicular glycoprotein (French and Ritzén, 1973; Danzo et al, 1974; Danzo and Black, 1990) that binds androgens with high affinity (Westphal, 1986) and transports ...