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DNA双链断裂（double strand break，DSB）是极为严重的DNA损伤形式。如果不对其进行修复或修复错误及修复不及时，可导致基因组突变和更大范围的结构重排，引起细胞癌变或者基因组不稳定性相关疾病等。
Evaluation of the Image-Pro Plus 4.5 software for automatic counting of labeled nuclei by PCNA immunohistochemistry
Image processing,computer-assisted Lichen planus Proliferating cell nuclear antigen
2009/10/20
The objective of this study was to create and evaluate a routine (macro) using Image-Pro Plus 4.5 software (Media Cybernetics, Silver Spring, USA) for automatic counting of labeled nuclei by prolifera...
In vitro and in vivo studies have shown that pressure treatment before decompression reduces bubble formation. This has been interpreted as evidence that bubbles originate from pre-existing gas nuclei...
Transformations of Sperm Nuclei Incorporated Into Aged and Unaged Hamster Eggs
pronuclear development aged and unaged ova
2009/2/19
The extent of male pronuclear development in aged and unaged hamster eggs was examined by electron microscopy. Observations are presented demonstrating that although hamster eggs, aged 18 hours in...
Thiol-disulfide status and acridine orange fluorescence of mammalian sperm nuclei
Spermatozoa maturation fertility protamine hamster acridine orange
2009/2/11
The relationship between thiol-disulfide status and acridine orange fluorescence of testicular, epididymal, and ejaculated spermatozoa in several mammalian species was investigated. Spermatozoa were...
Molecular Cytogenetic Detection of Meiotic Segregation Patterns in Sperm Nuclei of Carriers of 46,XY,t(15;17)(q21; q25)
Fluorescence in situ hybridization balanced translocation carrier
2008/12/15
Structural chromosomal abnormalities in gonadal tissue represent an important category of parentally transmittable unbalanced chromosomal abnormalities to the offspring. A child with multiple anomalie...