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Background: Osteoporosis is a disease, which causes bone loss and fractures. Although glucocorticoids effectively suppress inflammation, their chronic use is accompanied by bone loss with a tendency t...
Background: Emerging data suggest a significantly increased prevalence of low bone mineral density (BMD) in men and women with multiple sclerosis (MS) compared to age matched controls. This study was ...
Glucocorticoids, androgens, estrogens and 1 alpha,25-dihydroxycholecalciferol (1 alpha,25-(OH)2D3) exert a variety of effects on bone homeostasis. We have measured the receptors for these hormones...
Physical and psychosocial stress challenge homeostasis, increasing glucocorticoid secretion (in rodents, corticosterone [CORT]) while decreasing testosterone (T) levels. The dynamics of stress-induc...
Background: Glucocorticoid therapy can induce osteoporosis. Bone mineral density (BMD) measurement has been used to assess the risk of fracture in these patients. The most important mechanism is dimin...
In the past decade it has become clear that asthmatic patients who are clinically unresponsive, or ”resistant” to glucocorticoid therapy may have T cells which manifest resistance to glucocorticoid in...
Statement of Problem: Glucocorticoid-induced osteoporosis is characterized by a decrease in osteoblast numbers and a marked impairment of new bone formation. Purpose: The ain of present study was to e...

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