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FASE刊“Large Animal Stem Cells”专辑综述文章全面阐述猪多能性干细胞最新研究进展及科学展望（图）
FASE刊 Large Animal Stem Cells 综述文章 猪 多能性干细胞 动物育种应用
2019/3/12
多能干细胞（PSC）因其具有自我更新和多向分化潜能，在体外可以长期培养并能进行基因编辑，其在生命科学与医学领域，以及动物育种应用等领域备受青睐。然而，大家畜，如猪，至今没有获得能够进行生殖嵌合、稳定传代、体外长期培养的多能干细胞系。这也是制约大家畜育种的瓶颈。自第一株小鼠胚胎干细胞报道以来，科学家对猪多能干细胞进了30多年的攻关，虽取得了良好的进展，但仍存在急需解决的科学问题。近日，由中国农业大学...
Effects of Extracellular Matrix Protein-derived Signaling on the Maintenance of the Undifferentiated State of Spermatogonial Stem Cells from Porcine Neonatal Testis
Porcine Spermatogonial Stem Cells Undifferentiation, Extracellular Matrix Proteins
2016/11/10
In general, the seminiferous tubule basement membrane (STBM), comprising laminin, collagen IV, perlecan, and entactin, plays an important role in self-renewal and spermatogenesis of spermatogonial ste...
Isolation and Identification of Prepubertal Buffalo (Bubalus bubalis) Spermatogonial Stem Cells
Buffalo Spermatogonial Stem Cell Germ Cell Marker Proliferation
2016/11/10
Isolation and culture of spermatogonial stem cells (SSCs) are attractive for production of genetic modified offspring. In the present study, buffalo spermatogonial stem-like cells were isolated, cultu...
Differentiated Human Embryonic Stem Cells Enhance the In vitro and In vivo Developmental Potential of Mouse Preimplantation Embryos
Mouse Embryo d-hES Feeder Cell Co-culture Developmental Potential
2016/5/5
In differentiating human embryonic stem (d-hES) cells there are a number of types of cells which may secrete various nutrients and helpful materials for pre-implantation embryonic development. This st...
Chicken Stem Cells as a Model to Generate Transgenic Chicken:Present and Perspectives
blastoderm chicken germ cells pluripotency stem cell
2009/7/30
Over the past 3 decades, different strategies were launched to obtain transgenic animals and chicken in particular. Among various technical approaches, the direct modification of the embryo with DNA v...