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研究揭示mTORC1信号通路中SAMTOR感受SAM的分子机制（图）
mTORC1 SAMTOR SAM 分析机制
2022/9/13
2022年7月1日，Science Advances在线发表了中国科学院分子细胞科学卓越创新中心研究员丁建平研究组及其合作者的最新研究成果，题为Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling。该研究揭示了SAMTOR感知SAM（S-adenosylmethionine）以调控mTOR...
Regulation of mTORC1 by growth factors,energy status,amino acids and mechanical stimuli at a g lance
mTORC1 Akt Myostatin Muscle protein synthesis
2016/5/16
The mechanistic/mammalian target of rapamycin c omplex 1 (mTORC1) plays a pivotal r ole in the regulation of skeletal muscle protein synthesis. A ctivation of the c omplex leads to phosphorylation of ...
Patients with the genetic disorder tuberous sclerosis complex (TSC) suffer from neoplastic growths in multiple organ systems. These growths are the result of inactivating mutations in either the TSC1 ...