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端粒（Telomere）是真核细胞染色体末端的多重复序列（TTAGGG）及其结合蛋白组成的特殊结构（图1），主要功能是保护染色体末端免于降解、融合和退化，从而保证细胞DNA及相关遗传信息的稳定和完整。端粒长度（Telomere length, TL）随着细胞分裂次数的增加而不断缩短，当TL不能再缩短时，细胞也就无法继续分裂，进而走向衰老、死亡或癌变。因此，TL是指征衰老和疾病（糖尿病、肺纤维化、心...
You are cordially invited to participate in the conference on The PI3K-mTOR-PTEN Network in Health and Disease to be held at Cold Spring Harbor Laboratory. The opening session will begin at 7:30 pm on...
The role of the Borrelia oxidative stress regulator protein in virulence gene expression of the Lyme disease spirochete
Borrelia burgdorferi, BosR RpoS
2015/5/21
The Lyme disease agent, Borrelia burgdorferi, has a complex system that allows it to thrive in the harsh and distinct environments of its tick vector and mammalian host. Although it has been known for...
Queensland scientists provide insights into incurable brain disease
brain disease genetic condition
2014/7/11
Queensland Institute of Medical Research, Griffith University and University of Queensland scientists researching a degenerative brain disease have developed a new way to understand its progression an...
Development of Therapies to Treat Polycystic Kidney Disease
Polycystic Kidney Disease Lysophosphatidic Acid PPARγ agonists
2015/5/22
Polycystic kidney diseases (PKD) are genetic disorders characterized by fluid filled cysts in the kidney tubules and liver bile ducts. There are two forms of PKD, autosomal dominant polycystic kidney ...
A pioneering partnership between the University of Greenwich and the University for Modern Science and Arts in Cairo has seen a delegation of Egyptian students working in the laboratories of the Schoo...
ACE基因I/D多态与冠心病的遗传流行病学研究——表型不一致同胞对分析和传递不平衡检验The Insertion/Deletion Polymorphism of Angiotensin I Converting Enzyme Gene and Coronary Heart Disease——Discordant Sib Pair Analysis and Transmission/Disequilibrium Test
冠心病 遗传易感性 血管紧张素转换酶基因
2008/1/3
在冠心病家系中未发现ACE基因I/D多态与冠心病存在关联或与疾病基因座存在连锁，说明该基因座可能不是国人冠心病的遗传易患基因。
8 May 2007，University of Cambridge researchers have developed a novel strategy to tackle neurodegenerative diseases such as Huntington’s disease: encouraging an individuals own cells to “eat” the malf...