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Flipping a metabolic switch to slow tumor growth（图）
Flipping metabolic switch tumor growth
2020/8/27
An enzyme can be used as a metabolically responsive "switch" that decreases tumor growth, according to a new study. The findings are published in the journal Nature.By restricting the dietary ami...
Hormones, growth factors, and the regulation of tumor suppressor pathways involved in parity -induced protection of breast cancer
Women with breast cancer cases diagnosis and reproduction exogenous hormones ionizing radiation genetic factors
2014/12/11
Despite current advances in understanding breast cancer, in 2007 an estimated 178,480 new cases were diagnosed in female patients in the United States, and an estimated 40,640 deaths will occur due to...
From Mouse Mammary Tumor Model to New Therapeutic Method ---Mammary Tumor Development in Balb/c-Trp53+/- Mice and Magnetic Nanoparticle Induced Heating for Cancer Treatment
Breast cancer Magnetic nanoparticle Mammary gland Mouse tumor model Stem cell Thermotherapy
2014/12/10
PATHWAYS CONTRIBUTING TO DEVELOPMENT OF SPONTANEOUS MAMMARY TUMORS IN BALB/c-Trp53+/- MICE Mutation and loss of p53 function are common features among human breast cancers. We use BALB/c-Trp53+/- mice...
Regulation and Action of Skp2 and Rhoa in Cell and Tumor Models: Investigation into the Molecular Mechanisms Responsible for the Aggressive Phenotype of Triplenegative Breast Cancer
Basal-Like Breast Cancer Cell Cycle p27 proliferation SKP2 Triple-Negative Breast Cancer
2014/12/10
Breast cancer tops the list of new cancer cases and is predicted to be the second leading cause of cancer deaths in women in 2012. The primary objective of the present study was to provide insights in...
TRP-1 AS A MODEL TUMOR ANTIGEN FOR IMMUNOTHERAPY AND IMMUNE TOLERANCE IN THE THYMUS
immune tolerance T cells mTECs
2015/5/21
Tolerance mechanisms, which collectively work to prevent autoimmunity, play a key role in suppressing the adaptive immune response to tumor antigens. This phenomenon is attributed to the extensive ove...