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Imputing Missing Data for Gene Expression Arrays
Imputing Missing Data Gene Expression Arrays
2015/8/21
Here we describe three different methods for imputation.The first is based on a reduced rank SVD of the expression matrix, the second is based on K-nearest neighbor averaging, and the third is based o...
Averaged gene expressions for regression
Averaging Hierarchical clustering Lasso Variance reduction
2015/8/21
Although averaging is a simple technique, it plays an important role in reducing variance. We use this essential property of averaging in regression of the DNA microarray data, which poses the challen...
Molecular Distributions in Gene Regulatory Dynamics
Stochastic modelling；inducible/repressible operon
2010/12/16
We show how one may analytically compute the stationary density of the distribution of molecular constituents in populations of cells in the presence of noise arising from either bursting transcriptio...