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A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment
FOXP1 variant autism intellectual disability severe speech language impairment
2015/5/13
FOXP1 (forkhead box protein P1) is a transcription factor involved in the development of several tissues, including the brain. An emerging phenotype of patients with protein-disrupting FOXP1 variants ...
Increased Pain Intensity Is Associated with Greater Verbal Communication Difficulty and Increased Production of Speech and Co-Speech Gestures
Increased Pain Intensity Greater Verbal Communication Difficulty Speech Co-Speech Gestures
2015/5/6
Effective pain communication is essential if adequate treatment and support are to be provided. Pain communication is often multimodal, with sufferers utilising speech, nonverbal behaviours (such as f...
Researchers are beginning to uncover the neurogenetic pathways that underlie our unparalleled capacity for spoken language. Initial clues come from identification of genetic risk factors implicated in...
Neurogenomics of speech and language disorders: the road ahead
exome genome FOXP2 functional validation language next-generation sequencing neurodevelopmental disorders speech
2015/4/24
Next-generation sequencing is set to transform the discovery of genes underlying neurodevelopmental disorders, and so off er important insights into the biological bases of spoken language. Success wi...
The roles of bottom-up and top-down information in the recognition of reduced speech: Evidence from listeners with normal and impaired hearing
bottom-up top-down information
2015/4/10
Highly reduced pronunciation variants, such as something like ‘yeshay’ for yesterday, are abundant in
conversational speech. Previous research has shown that listeners understand such pronunciation
...