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2016冷泉港学术会议：泛素家族（Cold Spring Harbor conference on The Ubiquitin Family）
Systems Biology Proteasome
2017/1/19
We are pleased to host the ninth Cold Spring Harbor meeting on The Ubiquitin Family, which will will begin at 7:30 pm on Tuesday, April 18 and run through lunch on Saturday, April 22, 2017. The meetin...
The ubiquitin E3 ligase Human Homolog of Drosophila Ariadne-1 (HHARI) is a structural and functional homolog of Parkin and is required for myogenesis
Autosomal genes Parkinson's disease human beings parkinsonism E3 ubiquitin ligase neurons dopaminergic neurons
2014/12/11
Several genes implicated in Parkinson's disease (PD) encode components of the ubiquitin-proteasome pathway. In a specific form of PD (human Autosomal Recessive Juvenile Parkinsonism, AR-JP), loss of f...
Regulation of Notch signaling by the E3 ubiquitin ligase Cbl-b and its role in CD4+ T cell anergy
Cell life cycle T cell signal T cell activation and E3 ubiquitin ligase
2014/12/11
Notch signaling is an evolutionarily conserved pathway that mediates a variety of cell fate decisions. In the immune system, the Notch pathway plays an important role throughout the life of T cells. C...
The Parkin-like ubiquitin E3 ligase Ariadne-1 in the mammalian brain: Potential implications for neurodegenerative disease
Parkinson's disease movement disorders dopaminergic neurons gene encoding protein ubiquitin proteasome system enzyme E3 ubiquitin ligase
2014/12/10
Parkinson’s disease (PD) is a movement disorder characterized by a massive loss of dopaminergic neurons of nigrostriatal origins. Several genes associated with familial cases of PD encode proteins tha...
Expression Profiling of WSSV ORF 199 and Shrimp Ubiquitin Conjugating Enzyme in WSSV Infected Penaeus monodon
WSSV 199 Shrimp Ubiquitin Conjugating Enzyme Penaeus monodon)
2016/5/10
White spot syndrome virus (WSSV) is one of the major viral pathogens affecting shrimp aquaculture. Four proteins, WSSV199, WSSV 222, WSSV 249 and WSSV 403, from WSSV are predicted to encode a RING-H2 ...
Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy
gene expression Cullin 4
2007/2/9
6 February 2007，Recent investigation of Cullin 4 (CUL4) has ushered this class of multiprotein ubiquitin E3 ligases to center stage as critical regulators of diverse processes including cell cycle reg...