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Edge-Based Compartmental Modeling for Infectious Disease Spread Part III: Disease and Population Structure
Infectious Disease Part III Disease and Population Structure
2011/9/29
We consider the edge-based compartmental models for infectious disease spread introduced in .These models allow us to consider standard SIR diseases spreading in random populations. In this paper we s...
An Animal Model of Combined Pituitary Hormone Deficiency Disease
pituitary LHX3 endocrinology knock-in
2015/5/22
LHX3 is a LIM-homeodomain transcription factor that has essential roles in pituitary and nervous system development in mammals. Children who are homozygous for recessive mutations in the LHX3 gene pre...
Effects of Different Dietary Vitamin E Levels on Growth Performance, Non-specific Immune Responses, and Disease Resistance against Vibrio anguillarum in Parrot Fish (Oplegnathus fasciatus)
Vitamin E Requirement Immune Responses Vibrio anguillarum
2016/5/5
We report nutritional physiology and non-specific immune responses of vitamin E in parrot fish for the first time. This study aimed to investigate the essentiality and requirements in diets based on g...
A DNA test that reveals a person’s risk of certain diseases could be developed with technology created at the University.Scientists have developed a low-cost method of pinpointing variations in a pers...
Researcher wins NIH grant to study molecular components of disease
molecular components disease
2009/10/21
A University of Chicago researcher is among the first to win a new award from the National Institute of Health aimed at supporting research that “has the potential to transform the way we think about ...
A pioneering partnership between the University of Greenwich and the University for Modern Science and Arts in Cairo has seen a delegation of Egyptian students working in the laboratories of the Schoo...
Strategic China-Australian Neuroscience Program to research brain function and disease
Strategic China Australian Neuroscience Program brain function disease
2009/5/21
A unique China-Australian collaboration in neuroscience has been formed between UQ's Queensland Brain Institute (QBI) and The Institute of Biophysics (IBP), Chinese Academy of Sciences. A delegation o...
First descriptive study of an outbreak of Border disease in a sheep flock in Austria – a high risk factor for Bovine viral diarrhea virus free cattle herds: a case report
Border disease sheep cattle Austria
2015/3/17
Border disease is a congenital viral disease of
sheep and goats and was first reported in 1959 in
the Border region of Wales and England (Hughes
and Kershaw, 1959). The disease is characterised ...
Lipids in Health and Disease is an Open Access, peer-reviewed, online journal that publishes articles on all aspects of lipids: their biochemistry, pharmacology, toxicology, role in health and disease...
ACE基因I/D多态与冠心病的遗传流行病学研究——表型不一致同胞对分析和传递不平衡检验The Insertion/Deletion Polymorphism of Angiotensin I Converting Enzyme Gene and Coronary Heart Disease——Discordant Sib Pair Analysis and Transmission/Disequilibrium Test
冠心病 遗传易感性 血管紧张素转换酶基因
2008/1/3
在冠心病家系中未发现ACE基因I/D多态与冠心病存在关联或与疾病基因座存在连锁，说明该基因座可能不是国人冠心病的遗传易患基因。
人类单纯性先天性心脏病中TBX5基因的突变及表达研究 Studies on the Mutation and Expression of TBX5 Gene in Human Simple Congenital Heart Disease
TBX5基因 心脏发育 突变 表达
2007/12/31
摘要应用PCR-DGGE方法在61个单纯性先天性心脏病核心家系共216位成员中检测TBX5基因8个外显子的突变情况；以β-actin作为内对照对单纯性先天性心脏病患者（房间隔缺损12例、室间隔缺损16例、法洛四联症6例）和3个非先天性心脏病患者（正常对照）心肌标本进行RT-PCR扩增和定量分析，观察TBX5基因在mRNA水平有无差异。研究了人类单纯性先天性心脏病患者中TBX5基因突变及表达情况。在...
植物防御系统中抗病相关基因的研究进展Recent Advances in Research on Disease Resistance Genes in Defence System of Plant
R基因 R蛋白 无毒基因 基因克隆
2007/12/29
本文论述了植物防御系统中抗病相关基因（resistance gene,R基因）的研究进展。列表总结了迄今已克隆的R基因，并将其归为四种不同的类型。综述了不同基因表达产物-R蛋白在细胞中的定位及其相应的功能。此外，还对R基因编码区的多态性、R基因在染色体上排列方式以及R基因的进化与起源等问题进行了讨论。
基因敲除是研究生物体基因功能的有效手段。通过基因敲除建立的鼠疾病模型，在研究基因功能及人类疑难病症致病机制等方面发挥着前所未有的作用。本文对目前已获得的基因敲除鼠疾病模型进行了分类和总结，为相关研究的展开奠定了基础。
阿尔茨海默病中β淀粉样前体蛋白基因外显子9、10的mRNA表达及突变研究--Expression Variation and Mutation Analysis of Exon 9 and 10 in Amyloid Precursor Protein Gene in Alzheimer′s Disease
阿尔茨海默病 β淀粉样前体蛋白基因 表达 突变
2007/12/5
于上海地区汉人群中，探讨阿尔茨海默病(AD)患者外周血中β淀粉样前体蛋白基因外显子9、10（APP9~10）的mRNA表达水平，并作cDNA的点突变检测。采用半定量竞争性反转录聚合酶链反应(semi-quantitive competitive RT-PCR)技术测定APP9~10的mRNA表达水平；以聚合酶链反应（PCR）-限制性片段长度多态(RFLP)方法检测基因组DNA中载脂蛋白E基因(AP...
专著信息
书名
A new strategy to combat Alzheimer’s disease. Combining radical-scavenging potential with metal-protein-attenuating ability in one molecule
语种
英文
撰写或编译
作者
Hong-Fang Ji,Hong-Yu Zhang
第一作者单位
出版社...