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Recent work has shown that specific ALDH isoenzymes can contribute to the underlying pathology of different diseases. Many ALDH isozymes are important in oxidizing reactive aldehydes resulting from li...
ALDH isoenzymes are known to impact the sensitivity of certain neoplastic cells toward cyclophosphamides and its analogs. Despite its bone marrow toxicity, cyclophos-phamide is still used to treat var...
Over the past three years we have been involved in high-throughput screening in an effort to discover novel small molecular modulators of aldehyde dehydrogenase (ALDH) activity. In particular, we have...
Aldehydes are an important class of products from atmospheric oxidation of hydrocarbons. Isoprene (2-methyl-1,3-butadiene), the most abundantly emitted atmospheric non-methane hydrocarbon, produces a ...
A convenient and efficient application of heterogeneous La-containing SBA-15 systems for the microwave assisted oxidation of a lignin model phenolic monomer, 4-hydroxy-1-phenylpropane, is reported. Lo...
We have developed a simple, labor-saving, inexpensive, and rapid single nucleotide polymorphism (SNP) genotyping method that works directly on whole human blood. This single-tube genotyping method wa...
A polystyrene coated quartz crystal nanobalance (QCN) sensor was developed for use in the determination of a number of linear short-chain aliphatic aldehyde and ketone vapors contained in air. The qua...
Aldehyde oxidase (EC 1.2.3.1), a cytosolic enzyme containing FAD, molybdenum and iron-sulphur cluster, is a member of non-cytochrome P-450 enzymes called molybdenum hydroxylases which is involved in t...
Aldehydes and volatile organic compounds (VOCs) emission from plywood of various formaldehyde emission grades were measured using a small chamber method (JIS A 1901). The effect of the formaldehyde em...
Aldehydes and volatile organic compounds (VOCs) emitted from commercial laminated veneer lumber (LVL) were determined using the JIS small chamber method for 21 days. LVL samples were made from three ...
The long-chain alcohol and aldehyde contents and compositions were determined in seven types of the non-centrifuged cane sugar kokuto (Kokuto A to G). Long-chain alcohols, known as policosanols, have ...
摘要亚洲人群中普遍存在突变型的乙醛脱氢酶2(ALDH2*2)。此酶突变后活性缺失,导致乙醛在肝脏内大量累积使突变携带者在喝酒后会有脸红等不适反应,因此这可能影响他们的饮酒行为。由于ALDH2*2等位基因与饮酒行为相关,它也可能与酒精引起的肝脏损伤及某些癌症密切相关,而且,它在不同的亚洲人群中有不同的频率分布。近年来对ALDH2*2等位基因的序列结构、表达及其重要功能等有了更深入的了解,对ALDH2...

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