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【Soft Matter Lecture 135】Greener production approaches for therapeutic peptides（图）
Greener production therapeutic peptides Soft Matter Lecture
2023/6/19
【Soft Matter Lecture 135】Greener production approaches for therapeutic peptides
Global public health officials are concerned about the rise of drug-resistant bacterial and microbial infections, which are estimated to cause 10 million deaths each year by 2050, a crisis exacerbated...
2018年肽化学和生物学戈登研究会议（The 2018 Gordon Research Conference on Chemistry and Biology of Peptides）
2018年 肽化学和生物学戈登研究 会议
2018/1/12
Although more than a century has elapsed since the first synthesis of a dipeptide by Emil Fischer in 1901, the field of Peptide Science is more dynamic and vibrant than ever. The 2018 Chemistry and Bi...
Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study
glucose appetite food intake brake ileum duodenum GLP-1 PYY ghrelin
2018/11/19
Background: Activation of the ileal brake through the delivery of nutrients into the distal small intestine to promote satiety and suppress food intake provides a new target for weight loss. Evidence ...
Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study
glucose appetite food intake brake ileum duodenum GLP-1 PYY ghrelin
2018/11/16
Background: Activation of the ileal brake through the delivery of nutrients into the distal small intestine to promote satiety and suppress food intake provides a new target for weight loss. Evidence ...
2017年抗微生物肽戈登学术会议（The Gordon Research Conference (GRC) on Antimicrobial Peptides）
Antimicrobial Peptides
2017/1/19
The 2017 Antimicrobial Peptides GRC takes place 35 years after the pioneering report in Nature by Hans Boman and his colleagues of the discovery of cecropins (Steiner H, Hultmark D, Engström A, B...
Carp proteins as a source of bioactive peptides–an in silico approach
biological activity bioinformatics BIOPEP fish databases proteolysis
2016/5/11
In silico prediction methods and tools were used to determine whether bioactive peptides are hidden in the amino acid sequences of carp (Cyprinus carpio) proteins and whether they can be released afte...
Molecular “hats” allow in vivo activation of disguised signaling peptides
Molecular hats vivo activation disguised signaling peptides
2014/12/30
When someone you know is wearing an unfamiliar hat, you might not recognize them. Georgia Institute of Technology researchers are using just such a disguise to sneak biomaterials containing peptide si...
Synthetic Mimics Of Antimicrobial Peptides From Aryl Scaffolds
Pure sciences Amphiphilicity Antimicrobial peptides Immunomodulatory Smamps Suzuki coupling
2014/11/21
The rise in bacterial resistance and the declining approval rate of novel anti-infective drugs are a major threat to global public health. Antimicrobial peptides (AMPs), found in almost every multicel...
Optimization of Hydrolysis Conditions for Iron Binding Peptides Production from Shrimp Processing Byproducts
Iron Binding Peptides Production Hydrolysis
2016/6/2
Iron is one of the most popular trace elements in body and plays very important role in metabolism or construction of body. Organic iron from various sources for curing iron-deficiency anemia was one ...
Effects of metal ions and pH on the formation and decomposition rates of di- and tri-peptides in aqueous solution
salt-induced peptide formation metal ions copper (II) complex with glycine hydrothermal system prebiotic chemistry, origin of life
2017/4/11
The recent discovery of active deep-sea hydrothermal systems venting high-pH fluids suggests that the prebiotic chemistry
of the hydrothermal systems of early Earth may have been more diverse than pr...
Effects of Soybean Small Peptides on Rumen Fermentation and on Intestinal and Total Tract Digestion of Luxi Yellow Cattle
Microbial Rumen Fermentation Soybean Small Peptide
2016/5/11
Four Luxi beef cattle (400±10 kg) fitted with ruminal, duodenal and ileal cannulas were used in a 4×4 Latin square to assess the effects of soybean small peptide (SSP) infusion on rumen fermentation, ...
Effect of 24 h Fasting on Gene Expression of AMPK, Appetite Regulation Peptides and Lipometabolism Related Factors in the Hypothalamus of Broiler Chicks
Metabolism Nutrition Peptides Lipid Hypothalamus Broiler
2016/5/10
The 5’-adenosine monophosphate-activated protein kinase (AMPK) is a key part of a kinase-signaling cascade that acts to maintain energy homeostasis. The objective of this experiment was to investigate...
Temperature-Dependence of the Amide-I Frequency Map for Peptides and Proteins
Amide-I Frequency map Infrared spectrum Molecular dynamics simulation
2012/4/5
In our recent work [Phys. Chem. Chem. Phys. 11, 9149 (2009)], a molecular-mechanics force field-based amide-I vibration frequency map (MM-map) for peptides and proteins was constructed. In this work, ...
Development of Gastric and Pancreatic Enzyme Activities and Their Relationship with Some Gut Regulatory Peptides in Grazing Sheep
Digestive Enzymes Plasma Regulatory Peptides Grazing Lambs
2016/5/6
Forty-four Gansu Alpine Fine-wool lambs were used to study changes in the activities of three gastric and five pancreatic enzymes under grazing conditions between 0 and 56 days of age. The lambs were ...