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Free energy methods for efficient exploration of mixture posterior densities
Adaptive Biasing Force Adaptive Biasing Potential Adaptive Markov chainMonte Carlo Importance sampling Mixture models
2010/3/11
Because of their multimodality, mixture posterior densities are difficult to sample with
standard Markov chain Monte Carlo (MCMC) methods. We propose a strategy to enhance
the sampling of MCMC in th...
On Weight Matrix and Free Energy Models for Sequence Motif Detection
asymptotic efficiency discriminant analysis protein-DNA interaction predictive error transcription factor binding site
2010/3/9
The problem of motif detection can be formulated as the construction
of a discriminant function to separate sequences of a specific
pattern from background. In computational biology, motif detection...