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Association between human glutathione S-transferase omega rs4925 polymorphism and bladder cancer
Bladder Cancer Cigarette Smoking GSTO1 Polymorphism
2013/1/28
Glutathione S-transferases (GSTs) play an important role in the detoxification of polycyclic aromatic hydrocarbons and aromatic amines, the toxic substances contained in cigarettes. GST Omega 1 (GSTO1...
Survivin promoter rs9904341 polymorphism is associated with tumor stage and grade in patients with bladder cancer
Survivin Bladder Cancer Polymorphism Apoptosis
2013/1/28
Survivin is an inhibitor of apoptosis protein and also plays a important role in the development of several malignancies. To investigate the association between survivin promoter –31 G/C (rs9904341) p...
Impact of cytochrome P450 2C19*2 polymorphism on the clinical cardiovascular events after stent implantation in patients receiving clopidogrel of a southern Tunisian region
Clopidogrel CYP2C19*2 Polymorphism MACE Stent Thrombus
2013/2/19
Introduction: The concept of clopidogrel resistance, first described in biology is being strengthened by recent data from clinical epidemiology. The cardiologists have been sensitized to this concept ...
Polymorphism of Renalase Gene in Patients of Chronic Kidney Disease
Chronic Kidney Disease (CKD) Hypertension Hypertensive Nephrosclerosis
2013/1/31
Introduction: Chronic kidney disease (CKD) is an important public health problem. Early detection and treatment is a key factor for prevention of its complications. Hypertensive nephrosclerosis is a s...
Impact of obesity and Ala16Val MnSOD polymorphism interaction on lipid, inflammatory and oxidative blood biomarkers
Ala16Val MnSOD Polymorphism Obesity Oxidative Stress
2013/1/30
Previous investigations suggest association between obesity and Ala16Val MnSOD gene polymorphism. The V allele produces enzyme which not catalyze the superoxide anion efficiently as occurs with A alle...
A Common Polymorphism of Upstream Transcription Factor 1 Gene is associated with Lipid Profile: A Study in Chinese Type 2 Diabetes Families
dyslipidemia genetic epidemiology single nucleotide polymorphism type 2 diabetes mellitus upstream transcription factor
2009/10/30
Upstream transcription factor 1 (USF1) is capable of controlling various members in glucose and lipid metabolism pathways. Much evidence suggests that the rs3737787 polymorphism in the USF1 gene may l...
Increased Prevalence of Glycoprotein IIb/IIIa Leu 33 Pro Polymorphism in End Stage Renal Disease Patients on Hemodialysis
hemodialysis fibrinogen receptor polymorphism glycoprotein platelets CVD
2009/4/14
Traditional atherosclerosis risk factors cannot elucidate the increased prevalence of cardiovascular events in end stage renal disease (ESRD) patients on hemodialysis. A previous study has indicated a...
TP53 codon 72 Gene Polymorphism Paradox in Associated with Various Carcinoma Incidences, Invasiveness and Chemotherapy Responses
TP53 codon 72 apoptosis
2009/4/10
TP53 is the most common mutated gene in human cancers. Approximately half of all human malignancies exhibit TP53 mutations. The TP53 codon 72 polymorphism is a single-nucleotide polymorphism (SNP) in ...
Insertion/deletion polymorphism in the BRCA2 nuclear localization signal
Insertion/deletion polymorphism BRCA2 nuclear localization signal
2009/3/2
Mutations in human BRCA2 confer an increased risk of female breast cancer. In this study, we found a novel insertion/deletion polymorphism (10204insAAA causing amino acid change M3332IK) in canine B...