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Expressions of genes encoding drug-metabolizing enzymes are altered after sevoflurane, isoflurane, propofol or dexmedetomidine anesthesia
genes encoding drug-metabolizing enzymes sevoflurane isoflurane propofol dexmedetomidine anesthesia
2009/5/8
We previously showed that sevoflurane anesthesia affected the expression ratios of 177 of 10,000 genes in multiple organs of rats by microarray analyses. The maximum number of altered genes was dete...
The effects of dexmedetomidine on human neutrophil apoptosis
dexmedetomidine human neutrophil apoptosis
2009/3/2
The purpose of the present study was to evaluate the effect of dexmedetomidine, used as a sedative in the intensive care unit, on human neutrophil apoptosis and superoxide production in vitro. Neutr...