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A double-blind, placebo-controlled, glutamine-supplementation trial in growth-faltering Gambian infants
Glutamine growth intestinal permeability infants malnutrition immune response randomized control trial The Gambia
2008/12/25
Background: Growth faltering during infancy is a characteristic of life in developing countries. Previous studies have shown that small-intestine mucosal enteropathy, accompanied by endotoxemia and a ...
A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease
Gastroenterology celiac disease gluten toxicity small-intestinal morphometry gluten-free diet
2008/12/12
Background: Treatment of celiac disease (CD) is based on the avoidance of gluten-containing food. However, it is not known whether trace amounts of gluten are harmful to treated patients.Objective: Th...
Effects of probiotic therapy in critically ill patients: a randomized, double-blind, placebo-controlled trial1,2,3
Intestine multiple organ dysfunction syndrome Lactobacillus sp Bifidobacterium sepsis
2008/12/12
Background: Multiple organ dysfunction syndrome (MODS) is a major cause of mortality in intensive care units. A breakdown in gut barrier function and immune dysfunction are associated with the onset o...
An adaptogenic role for omega-3 fatty acids in stress; a randomised placebo controlled double blind intervention study (pilot) [ISRCTN22569553]
omega-3 fatty acids An adaptogenic role
2008/4/23
There is evidence for an adaptive role of the omega -3 fatty acid, docosahexaenoic acid (DHA) during stress. Mechanisms of action may involve regulation of stress mediators, such as the catecholamines...
Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study
bovine colostrum micronutrients
2008/4/23
Supplementation of nutritional deficiencies helps to improve immune function and resistance to infections in malnourished subjects. However, the suggested benefits of dietary supplementation for immun...
Effect of a natural extract of chicken combs with a high content of hyaluronic acid (Hyal-Joint®) on pain relief and quality of life in subjects with knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial
knee osteoarthritis
2008/4/23
Intra-articular hyaluronic acid represents a substantive addition to the therapeutic armamentarium in knee osteoarthritis. We examined the effect of dietary supplementation with a natural extract of c...
Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial
Phellodendron Magnolia
2008/4/23
Recent research has established correlations between stress, anxiety, insomnia and excess body weight and these correlations have significant implications for health. This study measured the effects o...
Nucleotide supplementation: a randomised double-blind placebo controlled trial of IntestAidIB in people with Irritable Bowel Syndrome [ISRCTN67764449]
double-blind Nucleotide supplementation
2008/4/23
Dietary nucleotide supplementation has been shown to have important effects on the growth and development of cells which have a rapid turnover such as those in the immune system and the gastrointestin...
Comparison of the effect of low-dose supplementation with L-5-methyltetrahydrofolate or folic acid on plasma homocysteine: a randomized placebo-controlled study
homocysteine plasma folate red blood cell folate,
2016/12/29
Food fortification with folic acid has been introduced in several countries for the prevention of neural tube defects. Fortification has lowered total homocysteine (tHcy) concentrations in the US popu...
Dietary counseling to increase natural folate intake:a randomized,placebo-controlled trial in free-living subjects to assess effects on serum folate and plasma total homocysteine
Folate folate intake homocysteine diet dietary counseling randomized trial community participants
2016/12/19
Background: The association between vascular disease and elevated plasma total homocysteine (tHcy) concentrations is caused, in part, by inadequate intakes of dietary folate. Increasing folate intake ...
A double-blind,placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia:effects on clinical response and nutritional status
Tuberculosis vitamin A zinc sputum smear conversion X-ray lesion area tuberculosis transmission micronutrient supplementation Indonesia
2016/12/17
Background: The results of cross-sectional studies indicate that micronutrient deficiencies are common in patients with tuberculosis. No published data exist on the effect of vitamin A and zinc s...
A randomized, placebo-controlled trial of the effect of zinc supplementation during pregnancy on pregnancy outcome in Bangladeshi urban poor
Zinc supplementation pregnancy pregnancy outcome low birth weight developing countries Bangladesh
2016/6/3
Background: Maternal zinc supplementation has been suggested
as a potential intervention to reduce the incidence of low
birth weight in developing countries. To date, placebo-controlled
trials have...