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De novo lipogenesis during controlled overfeeding with sucrose or glucose in lean and obese women
De novo lipogenesis deuterium overfeeding
2016/6/14
The results of previous studies suggest that de novo
lipogenesis may play an important role in the etiology of obesity,
particularly during overconsumption of different carbohydrates.
Site-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesity
Obesity central obesity cardiovascular risk
2016/6/14
Abdominal obesity is associated with coronary
risk, although causality is not well established.
Effects of weekly administration of pegylated recombinant human OB protein on appetite profile and energy metabolism in obese men
Obesity leptin OB protein
2016/6/14
Results of leptin administration in mice, rats, and
humans provide a rationale for therapeutic augmentation of circulating
leptin (OB protein) concentrations in obese humans;
this may reduce food i...
Resting metabolic rate in obese and nonobese Chinese Singaporean boys aged 13–15 y
fat mass fat-free mass analysis of covariance
2016/6/14
Previous studies investigating the hypothesis that
a low resting metabolic rate (RMR) is a cause of obesity yielded
discrepant findings. Two explanations for these findings are the
use of imprecise...
Energy density of foods affects energy intake across multiple levels of fat content in lean and obese women
Energy density fat content energy intake
2016/6/13
The results of previous studies indicated that
energy density, independent of fat content, influences energy
intake. In most studies, however, both fat content and energy
density were lower than in...
In animals, the whole-body content and accumulation
of linoleate can be measured and compared with its intake
to determine linoleate -oxidation. This method can also provide
quantitative informatio...
Short-term effects of weight loss with or without low-intensity exercise training on fat metabolism in obese men
fat oxidation energy restriction low-energy diet
2016/6/12
Energy restriction is known to induce a decline in
fat oxidation during the postdiet period. Reduced fat oxidation
may contribute to weight regain.
Whole-body and adipose tissue glucose metabolism in response to short-term fasting in lean and obese women
Abdominal obesity glucose uptake leptin
2016/6/12
Alterations in glucose metabolism during early
fasting may be an important trigger of the hormonal and metabolic
responses to fasting.
Moderate energy restriction increases bone resorption in obese postmenopausal women
energy restriction weight loss obesity
2016/6/12
Weight reduction reduces bone mineral density
(BMD) and increases the risk of osteoporosis.
Diurnal metabolic profiles after 14 d of an ad libitum high-starch, high-sucrose, or high-fat diet in normal-weight never-obese and postobese women
cardiovascular disease glycemia lipidemia
2016/6/12
The influence of the amount and type of carbohydrates
in the diet on risk factors for obesity, diabetes, and cardiovascular
disease remains unclear.
Effect of prolonged moderate and severe energy restriction and refeeding on plasma leptin concentrations in obese women
OB gene obesity leptin
2016/6/1
Plasma leptin in humans is subject to both longand
short-term regulation; it correlates with indexes of body fat
that can only change slowly. However, short-term fasting causes
large and rapid decr...
Body-composition changes with diet and exercise in obese women: a comparison of estimates from clinical methods and a 4-component model
weight loss body composition exercise
2016/5/31
Most methods available to clinicians for estimating
body-composition changes have been validated against estimates
from densitometry, based on a 2-component (fat mass and
fat-free mass) model.
Resting energy expenditure in reduced-obese subjects in the National Weight Control Registry
Obesity weight loss body composition
2016/5/31
Weight loss in obese subjects is associated with a
reduction in resting metabolic rate (RMR). Whether the reduction
can be explained solely by a reduction in lean body mass
remains controversial.
Effects of physical training and its cessation on the hemostatic system of obese children
Hemostatic factors D-dimer fibrinogen
2016/5/31
Physical training can improve hemostatic function
in adults, thereby reducing heart disease risk, but no information
is available in children on whether physical training can enhance
hemostatic fun...
Meta-analysis of resting metabolic rate in formerly obese subjects
Body composition fat-free mass fat mass
2016/5/31
A low resting metabolic rate (RMR) for a given
body size and composition is partly genetically determined and
has been suggested to be a risk factor for weight gain. Moreover,
a low relative RMR ha...