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“Your cancer has metastasized. I’m sorry,” is something no one wants to hear a doctor say.Cancer cells kill most often by crawling away from their original tumors to later re-root in vital parts of th...
Ovarian cancer (OC) is a lethal disease due to metastasis and chemoresistance. Our laboratory previously reported that tissue transglutaminase (TG2) is overexpressed in OC and enhances OC peritoneal m...
Unlike the great advances that have been made in reducing breast cancer mortality through the multidisciplinary treatment of primary disease, much less is understood about the natural history of metas...
Bone is a common site for cancer metastasis. The development of bone metastases represents a serious progression in a patient with cancer, leading to treatment goals changing from curative to palliati...
Cancer progression is characterised by extensive metabolic reprogramming. Renewed enthusiasm in this field has been sparked in part by the realisation that metabolic pathways, oncogenes and tumour sup...
Cancer remains a major cause of mortality, chiefly through metastatic spread of tumour cells to distant organs via the blood vascular or lymphatic circulations. The latter system has been more recentl...
Cancer arises from the deregulation of intracellular signaling pathways leading to uncontrolled cell proliferation and tumour formation. In many cases, cancer cells in the primary tumour disseminate a...
Leptomeningeal metastasis     Leptomeningeal  metastasis       2015/3/17
Leptomeningeal metastasis (LM) is usually a late complication of cancer, often accompanying systemic relapse of tumour. LM can affect any part of the neuraxis. It may seed the leptomeninges diffusely...
Background and objective Approximately 30% of patients who are diagnosed with non-small cell lung cancer (NSCLC) are classified as N2 on the basis of metastasis to the mediastinal lymph nodes. The eff...
Background and objective With the most recent introduction of microarray technology to biology, it becomes possible to perform comprehensive analysis of gene expression in cancer cell. In this study t...
We report a case of prostate cancer that was discovered by lymph node metastasis to along the common hepatic arterial nodes. The patient was a 72-year-old man who had undergone esophagectomy as surgic...

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