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肝癌是中国高发恶性肿瘤。由于其广泛的肿瘤异质性,最新的靶向联合免疫治疗的方案仅对20~30%的患者有效,并且缺乏指导精准用药的药敏分子分型。因此亟需研究可以指导肝癌精准用药的分子分型和揭示新的耐药靶点。
2023年12月2日,国家纳米科学中心聂广军研究员、李素萍研究员团队应邀对肿瘤进展过程中血小板的动态作用及其治疗意义进行了深入探讨和系统总结,相关综述以The dynamic role of platelets in cancer progression and their therapeutic implications为题在线发表于Nature Reviews Cancer期刊(Nature ...
2023年9月5日,癌症研究领域权威期刊Cancer Research(IF: 11.2)在线发表了题为"Genetic variants that impact alternative polyadenylation in cancer represent candidate causal risk loci"的研究论文[1]。武汉大学公共卫生学院博士后李斌、博士生蔡祎旻和谌灿为本论文的共同第一...
Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these c...
Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival fo...
In the five years since the FDA’s initial approval of chimeric antigen receptor (CAR) T cell therapy, Penn Medicine has gleaned 20 additional approvals related to drugs and techniques to treat or dete...
Every three to five days, all of the cells lining the human intestine are replaced. That constant replenishment of cells helps the intestinal lining withstand the damage caused by food passing through...
In what may turn out to be a long-missing piece in the puzzle of breast cancer, Harvard Medical School researchers have identified the molecular sparkplug that ignites cases of the disease currently u...
近日,中南大学湘雅医院癌变机理与靶向治疗研究中心肖志强教授团队在肿瘤免疫治疗学专业期刊“肿瘤免疫治疗杂志”《J Immunother Cancer》(IF: 12.469)上发表了题为“ANXA1-derived peptide for targeting PD-L1 degradation inhibits tumor immune evasion in multiple cancers”的原创...
A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers fou...
近日,中南大学湘雅医院肿瘤科周蓉蓉教授脑转移MDT团队在国际著名期刊Journal for ImmunoTherapy of Cancer(肿瘤免疫治疗期刊,IF=12.485)以论著形式在线发表了题为“Heterogeneity of tumor immune microenvironment of EGFR/ALK-positive tumors versus EGFR/ALK-negativ...
近日,中南大学基础医学院肿瘤研究所研究员陶永光团队与湘雅医院刘双研究员和肖德胜团队在国际肿瘤学期刊Molecular Cancer(IF=41.444)发表了题为“The chromatin‑associated RNAs in gene regulation and cancer(在基因表达和癌症中的染色质相关RNA)”的综述。肖德胜教授、刘双研究员和陶永光研究员为本论文的共同通讯作...
Immunotherapy — drug treatment that stimulates the immune system to attack tumors — works well against some types of cancer, but it has shown mixed success against lung cancer.
Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right...
Cancer is characterized by a number of key biological processes known as the “hallmarks of cancer,” which remodel cells and their immediate environment so that tumors can form, grow, and thrive. Many ...

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