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A novel fluorometric oligonucleotide assay to measure O 6-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpressing methylpurine DNA glycosylase
APE1/Ref-1 DNA repair status
2014/12/12
DNA repair status plays a major role in mutagenesis, carcinogenesis and resistance to genotoxic agents. Because DNA repair processes involve multiple enzymatic steps, understanding cellular DNA repair...
Aberrant methylation of Glutathione Stransferase P1 and E-cadherin in invasive ductal breast carcinoma and fibroadenoma
E-cadherin Breast invasive ductal carcinoma Fibroadenoma
2012/7/13
Objective To investigate the hypermethylation status of glutathione transferase P1(GSTP1) and E-cadherin (ECAD), TSGs (tumor suppressor genes) in our breast cancer samples and explore their correlatio...
Breast Carcinoma Showing Neuroendocrine Differentiation Characterized with Ectopic Hormone Production (2 case reports)
Neuroendocrine differentiation ectopic hormone production breast carcinoma
2009/6/29
Neuroendocrine differentiation can be found in benign or malignant lesions of various organ systems. In 1947, Vogler indicated the existence of neuroendocrine cells in mammary tissue (1). Recent studi...
BILATERAL EXUDATIVE RETINAL DETACHMENT SECONDARY TO BILATERAL CHOROIDAL METASTASIS OF BILATERAL BREAST CARCINOMA
Exudative retinal detachment choroidal metastasis
2010/4/6
Exudative retinal detachment (ERD) may be seen with many ocular pathologies including malignancies. Among malignant causes, metastases of breast and lung carcinoma are most common. A 50-year-old woman...