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Relationship Between Serum Hepcidin and Ferritin Levels in Patients With Thalassemia Major and Intermedia in Southern Iran
Hepcidin Hydroxyurea Ferritin Thalassemia Intermedia Thalassemia Major
2015/11/9
Background: Hepcidin is a key regulator of iron absorption in humans. It is mainly affected by hypoxia and iron stores.
Serum Ferritin Levels Correlation With Heart and Liver MRI and LIC in Patients With Transfusion-Dependent Thalassemia
Beta-thalassemia Ferritin Magnetic Resonance Imaging Liver Heart
2015/10/22
Background: Iron-loaded cardiac complication is the essential cause of mortality in patients with thalassemia. Early detection and treatment of cardiac over-load can reduce mortality.
The Prevalence of Zinc Deficiency in Patients With Thalassemia in South East of Iran,Sistan and Baluchistan Province
Thalassemia Major Zinc Iran
2015/10/14
Background: There are different and controversial reports about zinc deficiency in patients with major thalassemia.
Hydroxyurea Treatment in Transfusion-Dependent β-Thalassemia Patients
Hydroxyurea Blood Transfusion β-Thalassemia
2015/10/13
Background:: β-Thalassemia is an inherited hemoglobin disorder caused by defective synthesis of ß-globin chains. Hemoglobin (Hb) F induction is a possible therapeutic approach which can partially...
Transcranial Doppler Ultrasonography in Beta-thalassemia Major Patients Without and With Thrombocytosis
Beta-thalassemia Thrombocytosis Ultrasonography Doppler Transcranial
2015/9/29
Background: Beta-thalassemia is a type of anemia in which the patients may require splenectomy and this can lead to thrombocytosis with increased risk of stroke. Transcranial Doppler ultrasound is a m...
Combined α-thalassemia and Hemoglobin J-Iran (β77 His → Asp). A Family Study in southern Iran
Hb J-Iran α-thalassemia Hemoglobin variants Electrophoresis High performance liquid chromatography
2015/9/23
We report a 23-year-old man and three members of his family with Hb J-Iran confirmed by electrophoresis, chain separation by high performance liquid chromatography and sequencing. Alpha thalassemia wa...
Hemoglobin D (Hb D Punjab/ Los Angeles and Hb D Iran) and Co-Inheritance with Alpha- and Beta-Thalassemia in southern Iran
Hemoglobin (Hb) D Punjab Hb D Iran Hb D- beta- thalassemia (thal) Hb D-alpha- thal-1 trait Hb DSickle cell anemia
2015/9/23
Background: Hemoglobin-D (Hb D) is an uncommon structural hemoglobin variant, which is reported to be prevalent in north western India. There are only a few small series, of this entity in the literat...
Prediction of Heart Complications in Thalassemia Major Patients
Prediction Heart Complications Thalassemia Major Patients
2015/9/21
Beta thalassemia major is a chronic hemolytic anemia because of abnormal hemoglobin synthesis. These patients are at risk for iron overload and tissue intoxication. Heart failure is the most common an...
Thalassemia,Iron and G6PD Deficiency in Lor Migrating Nomad Children,Southern Iran
Frequency Iron deficiency Thalassemia G6PD deficiency Nomads Iran
2015/9/21
Background: Ferropenia and consequent iron deficiency anemia (IDA), β-thalassemia, and glucose 6-phosphate dehydrogenase (G6PD) deficiency are three main common hematologic problems in Iran. This stud...
Epidemiology of HCV Infection among Thalassemia Patients in Eastern Mediterranean Countries:a Quantitative Review of Literature
Systematic review Meta-analysis Thalassemia HCV EMRO Iran
2015/9/21
Background: Hepatitis C infection (HCV) is the major co-morbidity in thalassemia patients; however, literature lacks data from many EMRO counties. There is also enormous heterogeneity in the available...
Thalassemia: Incidence and predictive factors for chronic GVHD after HLA-identical sibling marrow transplantation
Thalassemia bone marrow transplantation chronic GVHD
2010/1/5
Allogeneic bone marrow transplantation is the only definie cure in thalassemia and its most important complication is chronic graft-versus-host disease (cGVHD). We analysed the incidence of cGVHD and ...
The prevalence of hypoparathyroidism among patients with major thalassemia aged above 10 years
Major thalassemia PTH trousseau Ferritin
2009/12/30
Background: Major Thalassemia is a chronic hemolytic anemia. It is the most common hemoglobinophathy disorder in Khuzestan province. Hypoparathyroidism is one of its endocrinologic complications due t...
Evaluation of the relationship of echocardiographic left vantricular mass to amounts of transfusions of packed cell and Deferoxamine in Thalassemia major
β-Thalassemia Left ventricular mass Ejection fraction Shortening fraction Packed cell Deferoxamine
2009/12/25
The disease of thalassemia major requires mangement by repeated transfusions of packed cell and iron chelators such as deferoxamine. Today, serum ferritin is used for estimation of adequacy of the man...
Serum Folate Level Determination in Major Beta Thalassemia Patients
Beta major thalassemia Folic acid Hemoglobin Folate Trace elements
2009/12/14
Objective: Beta major thalassemia is a variant of beta thalassemia syndrome which could be treated with bone marrow transplantation or if not available, regular blood transfusion. In the later group, ...
Rh Subgroups and Kell Antigens in Patients With Thalassemia and in Donors in Turkey
Blood subgroups thalassemia donors
2009/7/2
Alloimmunization can be a significant complication of transfusion therapy in patients with thalassemia and hemoglobinopathies. The aim of this study was to investigate Rh and Kell antigens in patients...