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评价Gene Xpert结核分枝杆菌/利福平(MTB/RIF,简称"Xpert")在人类免疫缺陷病毒(HIV)阴性肠结核患者早期快速诊断中的价值。方法:选取2018年1月至2019年6月在山东省胸科医院、北京胸科医院、苏州市第五人民医院3家医院就诊的254例HIV阴性疑似肠结核患者。采集所有患者的粪便标本,每份标本分别进行Xpert检测、涂片查抗酸杆菌、BACTEC MGIT 960(简称"MGI...
探讨Gene Xpert MTB/RIF检测(简称Xpert检测)在结核性胸膜炎诊断及利福平耐药检测中的应用价值。方法 回顾性分析2016年7月1日至2018年7月31日在西安市胸科医院外科就诊的86例初步诊断为结核性胸膜炎患者和同期 34例诊断为非结核胸膜炎患者的胸腔积液标本,分别行抗酸染色、BACTEC MGIT 960液体快速培养、荧光定量PCR和Xpert检测,对比4种方法检测结核分枝杆菌...
Background: Variations in intestinal antioxidant membrane transporters are implicated in the initiation and progression of inflammatory bowel disease (IBD). Facilitated glucose transporter member 14 (...
Introduction: Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine metabolism, which is caused by mutation in phenylalanine hydroxylase (PAH) gene. Most of the PAH mutations a...
Background: The relationship between decreased activity/neuropathic pain and gene expression alterations in soleus muscle has remained elusive.
Background: Atherosclerotic cardiovascular disease is currently a cause of mortality in some parts of the world. The ATP-Binding Cassette Transporter (ABCA1) gene prepares instructions to produce the ...
Genes can be activated or inhibited by signals within the tissues in response to an acute bout of exercise. It is unclear how a particular aerobic exercise bout may influence two muscles with similar ...
University of Queensland researchers have discovered that a gene that causes kidney disease also controls growth of the lymphatic system, a key route through which cancer spreads.
中国医学科学院实验血液学国家重点实验室王建祥课题组在在Leukemia期刊发表文章"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.”
Background: TNF-α as a pro-inflammatory cytokine play a key role in host defense against tuberculosis (TB). Presence of mutation in TNF-α gene can influence the effectiveness, performance and capabili...
Scientists at the Medical Research Council (MRC) have discovered that a gene called Sox9 plays a critical role in how stem cells behave and is crucial in the development of the central nervous system....
Background: Primary hemochromatosis is an inherited disorder. Mutation in this gene is accompanied with iron overload in the body leading to organ failure that primarily affects liver. Individuals wi...
Background: Pseudoexfoliation (PEX) syndrome leads to elevated intraocular pressure and consequent glaucomatous damage of the optic nerve. This study was performed to investigate the frequency of MTHF...
Aim: We aimed to assess vitamin-D receptor (VDR) gene polymorphism in postmenopausal osteoporotic Turkish women as well as the impact of this on diagnosis, treatment and quality of life. Materials and...
Aims: Dihydrofolate reductase (DHFR) is necessary for the reduction of the ingested folates before they are used in the body metabolism. Thus, the DHFR enzyme has an important role in folate supplemen...

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