搜索结果: 1-2 共查到“人体免疫学 CD40”相关记录2条 . 查询时间(0.133 秒)
激动型抗CD40单抗能够激活APC表面CD40免疫共刺激信号,促进其成熟和交叉提呈抗原并激活抗原特异性CTL以杀伤肿瘤,多年来一直是肿瘤免疫治疗的研究热点。以鼠源抗体为基础的研究表明,激动型抗鼠CD40单抗的活性受到抑制性Fcγ受体(FcγRⅡB)的驱动,但尚不清楚这一调控机制是否影响人类抗人CD40(hCD40) IgG单抗。为此,作者研究了Fcγ受体(Fcγ receptor, FcγR)结合...
Tolerance Induction by CD40 Silenced Dendritic Cells through Antisense
Dendritic cell Antisense CD40 Tolerance induction
2015/9/18
Background: One of the valuable tools for inhibiting the specific gene expression is antisense technique. To determine T cell responses, co-stimulatory molecule expression on the antigen presenting ce...