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Background: Recent reports suggest that small airway as well as large airway involvement in asthma is important. We investigate the therapeutic effects of a meter-dose inhaler of chrolofluorocarbon-be...
Background: Eosinophils are considered to be the major inflammatory cells in asthma. Since regulated on activation, normal T expressed and secreted (RANTES) is a potent chemoattractant for various imp...
Asthma is a disease of usually reversible airways obstruction that has prominent inflammation of the mucosa as an underlying feature. It is a disease of varying severity, with some individuals sufferi...
In the 1990s, the definition of asthma changed as we realized that asthma is fundamentally an inflammatory disorder. It was also shown in both adults and children that treatment should be initiated wi...
Following the re-administration of Pranlukast, the clinical symptoms disappeared within a few days and pulmonary function improved within 4 weeks. Eosinophils in the induced sputum almost completely d...
Inhaled corticosteroid therapy remains the basis for the treatment of chronic asthma. Recent understanding of its use includes the benefits of early introduction, and of its plateaued dose-benefit eff...
To investigate the relationship between local responsiveness and allergic symptoms, bronchial and nasal responsiveness were measured in the following four groups of subjects: (i) bronchial asthma pati...

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