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汕头大学医学院药理学课件 Histamine
Histamine is a biogenic amine widely distributed in the central nervous system that acts in a neuroregulatory role in controlling the waking state. The aim of this study was to determine whether 120 h...
SST significantly suppressed TDI-induced nasal allergy-like symptoms. TDI provocation showed a significant up-regulation of histamine H1 receptor (H1R) and histidine decarboxylase (HDC) gene expressio...
The release of RANTES and MCP-1 was significantly upregulated by histamine compared with the control group. Both carebastine and olopatadine inhibited the release of CC chemokine production to the con...
Eosinophilic airway inflammation and increased cough sensitivity without bronchial hyperresponsiveness are the pathologic and physiologic features of bronchodilator-resistant non-productive cough-asso...
We have shown that some patients presenting with chronic bronchodilator-resistant non-productive cough have global atopic tendency, airway cough hypersensitivity without non-specific bronchial hyperre...
On the basis of results from the present study, histamine, acting via H2 receptors, enhances the permeability of rat IgE across the RAEC mono-layer. The increased permeability of endothelial cells ind...
Although sulfidopeptide leukotrienes (sLT) are considered to play an important role in the pathogenesis of asthma, their precise action has not been elucidated in asthmatics during exacerbation. In th...
Background: Epinastine hydrochloride (epinastine) is a second-generation histamine H1-receptor antagonist widely used as an anti-allergic and anti-pruritic. To explore possible new aspects of the anti...
Although migraine affects about 15 % of the population, and many studies have been performed to find the mechanism and successful management, the physiopathology of migraine is still largely unknown. ...

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