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四川大学华西基础医学与法医学院药理学英文课件chapter10 Adrenoceptor antagonist drugs
四川大学华西基础医学与法医学院 药理学 英文课件 chapter10 Adrenoceptor antagonist drugs
2017/8/29
四川大学华西基础医学与法医学院药理学英文课件chapter10 Adrenoceptor antagonist drugs。
Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP
Fragile X mGluR MPEP audiogenic seizures open field fmr1
2015/8/3
Fragile X Syndrome is the most common form of inherited mental retardation worldwide. A Fragile X mouse model, fmr1, with a disruption in the X-linked Fmr1 gene, has three substantial deficits observe...
TNF-α Antagonist and Infection in Rheumatoid Arthritis
Inverse Probability Weighting Anti-TNF Infection Rheumatoid Arthritis
2013/1/31
Background: Anti-TNF treatment may increase infection risk, although this has been difficult to study because the timing of anti-TNF treatment is driven by disease activity, which may influence infect...
Microinjection of NMDA-type glutamate receptor agonist NMDA and antagonist D-AP-5 into the central nucleus of the amygdale alters water intake rather than food intake
NMDA受体 NMDA D-AP-5 杏仁中央核 食物摄取 水摄取
2012/6/28
目的探讨杏仁中央核中的N-甲基-D-天冬氨酸（NMDA）型谷氨酸受体对食物和水摄取的影响。方法不锈钢套管植入雄性Sprague-Dawley大鼠一侧杏仁中央核内，NMDA型谷氨酸受体激动剂原型物NMDA，或选择性NMDA受体拮抗剂D(?)-2-氨基-5-磷酰基戊酸（D-AP-5）微量注射入饱食和含水度正常的大鼠的杏仁中央核内。结果杏仁中央核内注射入8.50，17.00，或34.00 nmol NM...
Synthesis and Calcium channel antagonist activity of Nifedipine analogues with Chloroindolyl substituent
Synthesis Calcium channel antagonist activity Nifedipine analogues Chloroindolyl substituent
2010/1/6
Various diester analogues of nifedipine in which the ortho nitrophenyl group at position 4 were replaced by 3-chloro-1H-2-indolyl substituent, were synthesized and evaluated as calcium antagonists on ...
Synthesis and smooth muscle Calcium channel antagonist effect of Alkyl, Aminoalkyl 1,4-Dihydro-2,6-Dimethyl-4-Nitroimidazole-3,5 Pyridine Dicarboxylates
Ca+² channel antagonist DHP Arylpiperazine
2009/12/29
The discovery that 1,4-dihydropyridine (DHP) class of calcium channel antagonist inhibits the Ca+² influx represented a major therapeutic advance in the treatment of cardiovascular diseases such ...
Effects of KP-496, a Novel Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors, on Contractions Induced by Various Agonists in the Guinea Pig Trachea
antagonist anti-asthmatic drugs asthma leukotriene D4 thromboxane A2
2010/11/19
KP-496 produced parallel rightward shifts of the LTD4 and U46619 concentration-response curves in a concentration-dependent manner. Schild plot analyses of the antagonistic activities of KP-496 demons...
CONTROL OF ENVIRONMENTAL HEALTH AND REMOVAL OF RATS BY 2-ADRENERGIC ANTAGONIST AND POTASSIUM CHANNEL BLOCKER
KATP channel POTASSIUM CHANNEL BLOCKER
2010/4/6
In the present study, it is shown that in vivo oral administration of glibenclamide (1-10 mg/kg/day), an adenosine triphosphate -sensitive potassium channel blocker, and yohimbine (1-5 mg/kg/day), an ...
Effect of Epinastine Hydrochloride, a Second-generation Histamine H1-receptor Antagonist, on Sensory Neurons in vitro
epinastine histamine H1 antagonists nerve growth factor substance P
2010/11/22
Background: Epinastine hydrochloride (epinastine) is a second-generation histamine H1-receptor antagonist widely used as an anti-allergic and anti-pruritic. To explore possible new aspects of the anti...