搜索结果: 1-2 共查到“基础医学 CYP3A4”相关记录2条 . 查询时间(0.062 秒)
人细胞色素P450 3A4突变体CYP3A4.3, CYP3A4.4, CYP3A4.5和CYP3A4.18重组酶的异源表达与活性
细胞色素P450 CYP3A4 突变 杆状病毒科 睾酮
2009/11/26
目的 重组表达人细胞色素P450(CYP)3A4突变体CYP3A4.3, CYP3A4.4, CYP3A4.5和CYP3A4.18蛋白，为CYP3A4代谢活性的体外研究提供单一酶源。方法 应用杆状病毒表达系统构建含有各CYP3A4突变体基因序列的重组病毒，将其连同含人源还原型烟酰胺腺嘌呤二核苷磷酸-P450氧化还原酶（POR）和细胞色素b5基因的重组病毒共同感染昆虫草地夜蛾细胞Sf9得到CYP...
Common Cytochrome p4503A (CYP3A4 and CYP3A5) and Thiopurine S-Methyl Transferase (TPMT) Polymorphisms In Turkish Population
pharmacogenetics TPMT CYP3A4 CYP3A5
2009/6/22
Polymorphisms in the genes encoding cytochrome p450 (CYP) and thiopurine S-methyl transferase (TPMT) enzymes catalyze the metabolic reactions of several drugs.These polymorphisms might be responsible ...