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Effects of olopatadine hydrochloride on the release of thromboxane B2 and histamine from nasal mucosa after antigen-antibody reaction in guinea pigs
allergic rhinitis chemical mediators guinea pigs olopatadine
2010/11/25
Background: Various mediators, such as thromboxane (TX) A2, peptide leukotrienes (P-LT) and histamine, are involved in allergic nasal obstruction. The aim of the present study was to investigate the m...
Sulfidopeptide leukotrienes, but not thromboxane B2 or histamine, are elevated in sputum during exacerbation of asthma
asthma histamine sputum sulfidopeptide leukotrienes thromboxane B2
2010/11/25
Although sulfidopeptide leukotrienes (sLT) are considered to play an important role in the pathogenesis of asthma, their precise action has not been elucidated in asthmatics during exacerbation. In th...
Urinary leukotriene E4 and 11-dehydro-thromboxane B2 excretion in children with bronchial asthma
bronchial asthma cysteinyl leukotrienes 11-dehydro-thromboxane B2 leukotriene E4 thromboxane A2
2010/11/22
Urinary LTE4 levels during an acute attack (median 476 pg/mg creatinine; range 191-1100 pg/mg creatinine) and during the stable condition (median 332 pg/mg creatinine; range 128-965 pg/mg creatinine) ...