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Round spermatids show normal testis-specific H1t but reduced cAMP-responsive element modulator and transition protein 1 expression in men with round-spermatid maturation arrest
ene expression human testis spermatogenic impairme
2009/2/18
During spermiogenesis, histones are replaced by transition proteins, which in turn are replaced by protamines. The TNP1 gene-encoding TP1 (transition protein 1) protein contains a cAMP-responsive el...
Follicle-stimulating hormone and testosterone stimulation of immature and mature Sertoli cells in vitro：inhibin and N-cadherin levels and round spermatid binding
Follicle-stimulating hormone testosterone stimulation immature mature Sertoli cells
2009/2/18
The in vitro response of Sertoli cells isolated from adult rat testes to testosterone (T) and follicle-stimulating hormone (FSH) treatment was investigated. Sertoli cells from >70-day-old Sprague-...
The acid-fast stain is a superior stain for use in the mean mature spermatid count for testicular biopsies
Male infertility spermatogenesis obstructive azoospermia
2009/2/17
The mean mature spermatid count (MMSC) provides a useful, simplified quantitative evaluation of human spermatogenesis that is based on the number of mature spermatids in histological sections of t...
The Sertoli-Spermatid Junctional Complex Adhesion Strength Is Affected In Vitro by Adjudin
Ectoplasmic specialization testis micropipette adherens junction male contraception
2008/12/24
The actin-based cell-cell adherens junction (AJ) between the Sertoli cell and the germ cell in the mammalian testis is important not only in mechanical adhesion of the cells, but in the morphogen...
Strength Measurement of the Sertoli-Spermatid Junctional Complex
Ectoplasmic specialization testis micropipette adherens junction
2008/12/23
The Sertoli cell ectoplasmic specialization (ES) is a specialized domain of the calcium-dependent Sertoli cell-spermatid junctional complex. Not only is it associated with the mechanical adhesion of...
Cloning and Characterization of Rat Spermatid Protein SSP411: A Thioredoxin-Like Protein
Thioredoxin spermatogenesis testis gene cloning
2008/12/22
In an attempt to identify new sperm-specific genes that are involved in sperm maturation, fertilization, and embryo development, such as the mammalian ortholog of the sperm-supplied protein gene, sp...
Intracytoplasmic Spermatid Injection Can Result in the Delivery of Normal Offspring
Nonobstructive azoospermia TESE ICSI
2008/12/19
Almost one-third of all patients with nonobstructive azoospermia undergoing testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI) have cancelled cycles due to failure to fin...