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非酒精性脂肪性肝病(NAFLD)包括从单纯脂肪变性到非酒精性脂肪性肝炎(NASH)等不同严重程度的肝脏病变,而NASH可发展为肝硬化并最终发展为肝细胞癌,是当前全球肝移植和肝脏相关死亡率的主要因素之一。然而,目前还没有药物被批准用于非酒精性脂肪肝的临床治疗。肝脏中脂肪酸从头合成(DNL)速率的增加是非酒精性脂肪性肝病的一个显著特征。先前的研究表明,抑制脂肪酸从头合成中的限速酶乙酰辅酶a羧化酶(AC...
Till January 20, 2020, the 2019-new coronavirus (2019-nCoV) has caused more than one hundred cases in Wuhan (WMHC 2020). During a retrospective study of recent pneumonia patients in our department, we...
The 2017-2018 AACP Professional Affairs Committee addressed the charges of (1) developing a self-reflection/self-assessment tool for pharmacy faculty and preceptors to allow them to assess their capab...
The Argus Commission examined the National Academy of Medicine’s publication “Vital Directions for Health and Health Care” and engaged with six guests from outside academic pharmacy to identify the sa...
The 2017-2018 American Association of Colleges of Pharmacy (AACP) Student Affairs Standing Committee addressed charges related to student wellness and resilience and identified ways where AACP can ass...
Student engagement is key to the success of schools and colleges of pharmacies in meeting their mission and programmatic needs. Student engagement in the pharmacy profession often occurs before accept...
The 2017-2018 Research and Graduate Affairs Committee (RGAC) was given three charges aimed at helping academic pharmacy address barriers that must be overcome by both students and schools to attract, ...
Objective. To characterize informatics education opportunities in US colleges and schools of pharmacy curricula. Methods. Informatics curricular information online was catalogued via publicly availab...
Abraham Flexner’s 1910 report on medical education in the United States (US) and Canada propelled medical training forward into a contemporary renaissance. The report heralded many seismic changes tha...
Observational studies suggested that breastfeeding benefits the visual development of preterm children, which has been attributed to the presence of docosahexaenoic acid (DHA) in breast milk but no...
On 6 and 7 May 1999, a group of researchers from 10 countries met in Atlanta to contemplate the simplified use of anthropometry to assess the risk of chronic disease associated with overweight and ...
This American Society for Nutritional Sciences Controversy Session presented at the 1997 Experimental Biology meeting considered whether publicity of findings from single studies facilitates or ham...
A workshop was convened in 1997 by the National Institutes of Health and the Centers for Disease Control and Prevention to consider the need for and feasibility of conducting a randomized clinical ...
Introduction: Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine metabolism, which is caused by mutation in phenylalanine hydroxylase (PAH) gene. Most of the PAH mutations a...
Introduction: Ventriculoperitoneal (V-P) shunt surgery is the most common technique used for the treatment of hydrocephalus. The migration of ventriculoperitoneal shunt to the bladder is rare. Only tw...

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