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Antitussive Effects of the Leukotriene Receptor Antagonist Montelukast in Patients with Cough Variant Asthma and Atopic Cough
atopic cough cough score cough variant asthma leukotriene receptor antagonist montelukast
2010/11/12
In patients with CVA, 2-week treatment with montelukast, clenbuterol, and montelukast plus clenbuterol all significantly decreased cough scores and treatment with montelukast plus clenbuterol was supe...
Population-based open-label clinical effectiveness assessment of the cysteinyl leukotriene receptor antagonist pranlukast
asthma pranlukast questionnaire symptom treatment
2010/11/26
Although the efficacy of cysteinyl leukotriene receptor antagonists in asthma therapy has been established through controlled clinical trials, there are no data concerning the effectiveness of their u...
Effect of a leukotriene receptor antagonist, pranlukast hydrate, on airway inflammation and airway hyperresponsiveness in patients with moderate to severe asthma
airway hyperresponsiveness airway inflammation asthma eosinophils leukotriene leukotriene receptor antagonist
2010/11/25
Asthma is characterized by chronic airway inflammation and the recruitment of inflammatory cells, typically eosinophils and lymphocytes, into the airway. Although several chemical mediators are releas...
Effect of a leukotriene receptor antagonist on the prevention of recurrent asthma attacks after an emergency room visit
β2-adrenergic receptor agonist asthma exacerbation leukotriene receptor antagonist montelukast
2010/11/24
In the montelukast group, the need for a rescue β-adrenergic receptor agonist was significantly decreased; 54.5% of patients in the montelukast group required use of β-adrenergic receptor agonist comp...
Effect of Epinastine Hydrochloride, a Second-generation Histamine H1-receptor Antagonist, on Sensory Neurons in vitro
epinastine histamine H1 antagonists nerve growth factor substance P
2010/11/22
Background: Epinastine hydrochloride (epinastine) is a second-generation histamine H1-receptor antagonist widely used as an anti-allergic and anti-pruritic. To explore possible new aspects of the anti...
Effect of a leukotriene receptor antagonist on cough receptor sensitivity and allergen-induced cough in a patient with atopic cough variant asthma
asthma atopy cough variant asthma leukotriene receptor antagonist
2010/11/29
A 24-year-old female patient with chronic dry cough, without wheezing and other symptoms, was diagnosed as atopic cough variant asthma (CVA) sensitized with house dust (HD) mite. To investigate the ef...
Effect of a thromboxane A2 receptor antagonist, ramatroban (BAY u 3405), on inflammatory cells, chemical mediators and non-specific nasal hyperreactivity after allergen challenge in patients with perennial allergic rhinitis
eosinophil nasal allergen challenge nasal mucosal reactivity perennial allergic rhinitis ramatroban thromboxane A2 receptor antagonist
2010/11/29
In some clinical studies performed in patients with perennial allergic rhinitis, ramatroban, a new thromboxane A2 receptor antagonist, significantly improved nasal symptoms. As yet the mechanism of ac...