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Evolving clinical profile of HLA-DRB1,MMP1 and NF-Κb gene in rheumatoid factor positive Caucasian population
Rheumatoid arthritis Rheumatoid factor HLA-DRB1 MMP1 NFkB1
2015/7/22
Rheumatoid arthritis (RA), a systemic autoimmune condition, causes joint damage and sometimes extra-articular lesions (cutaneous vasculitis, neuropathy, Felty’s syndrome, pericarditis, intersticial lu...
MMP1过表达的骨髓间充质干细胞对肝纤维化的修复作用
基质金属蛋白酶1 基因治疗 肝纤维化
2014/4/22
探讨基质金属蛋白酶1(matrix metalloproteinase 1，MMP-1)过表达的骨髓间充质干细胞(bone marrow mesenchymal stem cells，BMSCs)对大鼠肝纤维化修复作用的影响。方法：50只雄性SD大鼠随机分为4组，重组腺病毒Ad-人MMP-1(human MMP-1，hMMP-1)-增强绿色荧光蛋白(enhanced green fluoresce...