搜索结果: 1-15 共查到“医学 LHRH”相关记录24条 . 查询时间(0.14 秒)
Mechanism of LHRH-stimulated steroidogenesis in rat Leydig cells：lipoxygenase products of arachidonic acid may not be involved
LHRH-stimulated steroidogenesis rat Leydig cells lipoxygenase products arachidonic acid
2009/2/23
Luteinizing hormone releasing hormone agonist, [(imBzl)-DHis6,Pro9,NEt]-LHRH (LHRH-A), caused a two to threefold increase in in vitro testosterone (T) secretion by rat Leydig cells. This LHRH-A-indu...
Pituitary response to LHRH during chronic renal insufficiency in the male rat
Pituitary LHRH chronic renal insufficiency male rat
2009/2/23
Chronic renal insufficiency was induced in young adult male rats by a 2-step 5/6 nephrectomy. Four weeks after surgery the rats were anesthetized with ketamine and injected with saline or 1, 5, 10...
Reversal of testicular function after prolonged suppression with an LHRH agonist in rhesus monkeys
testicular function prolonged suppression LHRH agonist rhesus monkeys
2009/2/23
Using subcutaneously implanted osmotic pumps, four male rhesus monkeys were continuously infused for 18 months with 100 micrograms/day of [(imBzl)-D-His6-Pro9-NEt]-LHRH (LHRH-A), a potent agonist of...
Heterogeneity of sperm density profiles following 16-week therapy with continuous infusion of high-dose LHRH analog plus testosterone
sperm density profiles 16-week therapy high-dose LHRH testosterone
2009/2/23
LHRH agonist analogs have been investigated as potential male contraceptives. It has been shown that the LHRH agonistic analog [D-Trp6,Pro9-NEt] LHRH (LHRHA) given to men in single doses up to 500 m...
Lack of correlation between fertility and sperm numbers in male rats treated with histrelin, a potent LHRH agonist
correlation fertility sperm numbers male rats histrelin potent LHRH agonist
2009/2/23
Adult male rats were treated daily for up to 8 weeks with histrelin, [(ImBzl)-D-His6, Pro9-NEt]LHRH, to study the antifertility effects of this LHRH agonist. Although serum testosterone concentratio...
Dose-response studies on male reproductive parameters in dogs with nafarelin acetate, a potent LHRH agonist
LHRH agonist nafarelin acetate EDNal(2)6JLHRH spermatogenesis prostate male dogs
2009/2/20
Adult male beagle dogs were administered daily subcutaneous injections of either 0.5 or 2.0 micrograms/kg of a potent LHRH agonist, nafarelin acetate, for 44 days. Although there was a rise in the c...
Recovery of gonadal functions in the adult male rat following cessation of five-month daily treatment with an LHRH agonist
LHRH agonist testicular steroidogenesis ventral prostate seminal vesicles spermatogenesis
2009/2/20
This study describes the recovery of various parameters of the pituitary-gonadal axis following five months of daily treatment of adult male rats with a potent LHRH (luteinizing hormone-releasing ...
Heterogeneity of sperm density profiles following 20-week therapy with high-dose LHRH analog plus testosterone
LHRH analog sperm density heterogeneous response
2009/2/20
Eight normal male volunteers received an LHRH analog, 100 to 500 micrograms daily, for 20 weeks. Testosterone enanthate, 100 mg, was given by injection every second week. Sperm density fell to 5.5 X...
Effects of an LHRH agonist analog upon sexual function in male dogs. Suppression, reversibility, and effect of testosterone replacement
LHRH agonists D-Na!(2)6-LHRH spermatogenesis
2009/2/20
Male beagle dogs were injected once daily with 10 micrograms/kg of [6-D-(2-naphthyl)alanine]-LHRH (D-Nal(2)6-LHRH), a potent LHRH agonist, for periods up to 42 days, with recovery periods up to 172 ...
Combined treatment with an LHRH agonist and testosterone in man. Reversible oligozoospermia without impotence
LHRH (GnRH) testosterone spermatogenesis
2009/2/19
We have previously shown that LHRH agonist [D-Trp6,Pro9-NEt]LHRH (LHRHA) results in reversible oligozoospermia when given to normal subjects for up to ten weeks. A fall in plasma testosterone was ac...
Inability of continuous long-term administration of D-Nal（2）6-LHRH to abolish fertility in male rats
D-Nal(2)6-LHRH fertility male rats
2009/2/19
A highly potent agonist of LHRH, [6-D-(2-naphthyl)-alanine]-LHRH, was administered chronically for 12 weeks to adult male rats by repetitive implantation of pellets, and its effects upon mating, fer...
Animal model of isolated gonadotropin deficiency. II. Morphologic responses to LHRH immunoneutralization
hypogonadotropic-hypogonadism LHRH dog immunohypophysectomy testis prostate excurrent
2009/2/19
Morphologic changes in the male reproductive system of mongrel dogs immunized against LHRH were quantitated using linear measurements and morphometric techniques at the light-microscopic level. Two ...
Animal model of isolated gonadotropin deficiency. I. Hormonal responses to LHRH immunoneutralization
hypogonadotropic-hypogonadism luteinizing hormone releasing hormone pituitary serum LH
2009/2/19
Five intact male mongrel dogs, characterized by an episodic secretory pattern of LH and normal serum testosterone concentrations, were actively immunized against LHRH by subcutaneous injections of 2...
In Vivo and In Vitro Investigation of the Extrapituitary Antireproductive Effects of a Potent LHRH Agonist in Immature and Adult Male Rats
LHRH agonist extrapituitary reproductive effects age-dependency hypophysectomy
2009/2/19
Co-incubation with a potent LHRH agonist, D-Ala6-Des-Gly10-Pro9-NHEt-LHRH (Wy-18,481), did not affect testosterone or progesterone production by adult intact rat testes in vitro. Prior administrat...
Effects of Chronic, High-dose LHRH-Agonist Treatment on Pituitary and Testicular Functions in Rhesus Monkeys
Chronic High-dose LHRH-Agonist Treatment Pituitary Testicular Functions Rhesus Monkeys
2009/2/18
The effects of chronic, high-dose treatment with an LHRH-agonist (D-Ser-(TBu)6-LHRH-ethylamide) on pituitary and testicular functions were investigated in four adult rhesus monkeys in-season. Doses ...