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Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo: Role of the C-terminal polybasic domain
Rac GTPase NADPH oxidase
2014/12/12
The Rho family GTPase Rac acts as a molecular switch for signal transduction to regulate various cellular functions. Mice deficient in the hematopoietic-specific Rac2 isoform exhibit agonist-specific ...
Cytoplasmic extrusion and the switch from creatine kinase B to M isoform are completed by the commencement of epididymal transport in human and stallion spermatozoa
Maturity and function men stallions fertility cytoplasmic
2009/2/17
Although in several species there is a relationship between epididymal sperm transport and fertility, in human in vitro fertilization (IVF), spermatozoa recovered from the caput epididymidis or ev...
Expression and localization of the Na+/H+ exchanger isoform NHE3 in the rat efferent ducts
Absorption fluid immunohistochemistry reverse transcription-polymerase chain reaction Western blot
2008/12/30
The efferent ducts reabsorb most of the fluid released with spermatozoa from the testis. This absorptive capacity results in a severalfold increase in sperm concentration in the proximal epididymis ...
Stage-Specific Expression of the Atce1/Tisp40 Isoform of CREB3L4 in Mouse Spermatids
AIbZIP endoplasmic reticulum unfolded protein response
2008/12/24
The maturation of haploid spermatids into spermatozoa relies on the timely production of proteins required for spermatid differentiation. The mammalian CREB3L4 (cAMP responsive element binding pr...
Receptor Isoform and Ligand-Specific Modulation of Dihydrotestosterone-Induced Prostate Specific Antigen Gene Expression and Prostate Tumor Cell Growth by Estrogens
Androgen receptor androgens estrogen receptor
2008/12/23
Androgens via the androgen receptor (AR) play crucial roles in prostate physiology and pathophysiology. These androgen actions can be either inhibited or potentiated by estrogens. The mechanisms of ...
Detection of a Short CCR5 Messenger RNA Isoform in Human Spermatozoa
Sperm mRNA CCR5 RQ-PCR
2008/12/22
It has recently been reported that the Regulated upon Activation of Normal T-cells Expressed and Secreted (RANTES) chemokine may exhibit a chemotactic effect on sperm. The RANTES chemokine acts on t...
Expression and localization of the Na+/H+ exchanger isoform NHE3 in the rat efferent ducts
Expression localization Na+/H+ exchanger NHE3 rat ducts
2008/12/2
The efferent ducts reabsorb most of the fluid released with spermatozoa from the testis. This absorptive capacity results in a severalfold increase in sperm concentration in the proximal epididymis ...
EXPRESSION OF CELLULAR ISOFORM OF PRION PROTEIN ON THE SURFACE OF PERIPHERAL BLOOD LYMPHOCYTES AMONG WOMEN EXPOSED TO LOW DOSES OF IONIZING RADIATION
radiation exposure cellular isoform of prion lymphocytes
2010/12/23
Ionizing radiation affects the expression of adhesive and co-stimulatory molecules in lymphocytes. The physiological function of cellular isoform of prion protein (PrPc) is little known.