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Coffee consumption after myocardial infarction and risk of cardiovascular mortality: a prospective analysis in the Alpha Omega Cohort
coffee myocardial infarction patients cardiovascular disease ischemic heart disease mortality prospective cohort study
2018/11/20
Background: Consumption of coffee, one of the most popular beverages around the world, has been associated with a lower risk of cardiovascular and all-cause mortality in population-based studies. Howe...
Dietary fatty acid intake after myocardial infarction: a theoretical substitution analysis of the Alpha Omega Cohort
dietary fatty acids cardiac patients cardiovascular disease
2018/11/19
Background: Replacement of saturated fatty acids (SFAs) with unsaturated fatty acids (UFAs), especially polyunsaturated fatty acids (PUFAs), has been associated with a lower risk of ischemic heart dis...
Dietary fatty acid intake after myocardial infarction: a theoretical substitution analysis of the Alpha Omega Cohort
dietary fatty acids cardiac patients cardiovascular disease coronary heart disease substitution analysis prospective cohort study
2018/11/16
Background: Replacement of saturated fatty acids (SFAs) with unsaturated fatty acids (UFAs), especially polyunsaturated fatty acids (PUFAs), has been associated with a lower risk of ischemic heart dis...
The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
Alpha glycerylphosphorylcholine Strength Human performance Sport supplements
2015/12/2
Ergogenic aides are widely used by fitness enthusiasts and athletes to increase performance. Alpha glycerylphosphorylcholine (A-GPC) has demonstrated some initial promise in changing explosive perform...
Alpha-Amanitin Poisoning, Nephrotoxicity and Oxidative Stress: An Experimental Mouse Model
Alpha-Amanitin Oxidative Stress Mycotoxins
2015/11/9
Background: Alpha-amanitin (α-AMA) plays a major role in Amanita phalloides poisoning, showing toxic effects on multi-organs, particularly on the liver and kidneys. Studies have shown a relationship b...
A Comparison of Dexmedetomidine, Moxonidine and Alpha-Methyldopa Effects on Acute, Lethal Cocaine Toxicity
Cocaine Intoxication Dexmedetomidine Moxonidine Alpha-Methyldopa
2015/11/6
Background: The treatment of cocaine toxicity is an important subject for emergency physicians. We investigated the effects of dexmedetomidine, moxonidine and alpha-methyldopa on acute cocaine toxicit...
Tumor Necrosis Factor-Alpha Polymorphism and Susceptibility to Multiple Sclerosis in the Iranian Population
Tumor Necrosis Factor-Alpha Multiple Sclerosis Sclerosis
2015/10/16
Background: Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology. Tumor necrosis factor-α (TNF-α) microsatellite as a proinflammatory cytokine is believed to play an important r...
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men
Resistance exercise Ergogenic aids Nitric oxide
2015/7/23
Dietary supplements containing L-arginine are marketed to improve exercise performance, but the efficacy of such supplements is not clear. Therefore, this study examined the efficacy of acute ingestio...
Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects
Alpha-Klotho ELISA Calcium Phosphate
2014/12/11
Background α-Klotho (αKl) regulates mineral metabolism such as calcium ion (Ca2+) and inorganic phosphate (Pi) in circulation. Defects in mice result in clinical features resembling disorders found in...
Production of Recombinant Alpha Neurotoxin of Scorpion Venom Mesobuthus eupeus and Analysis of its Immunogenicity
Venoms Neurotoxin Scorpion Recombinant Protein
2015/10/10
Background:: Scorpion venom is important and rich source of peptides, most of which have been widely used as pharmacological tools for unraveling structure-function relationship of various ion channel...
Tumor Necrosis Factor-Alpha Polymorphism at Position -238 in Preeclampsia
Tumor Necrosis Factor-Alpha Pre-Eclampsia Polymorphism Genetic
2015/10/10
Background:: Preeclampsia is the most common serious disorder during pregnancy and studies show several immune-related processes in its pathophysiology. The role of cytokines and their expression rema...
目的：构建包含不同Alpha基因片段的重组报告质粒和Alpha1-TFEB 融合基因表达质粒，并评价Alpha基因启动子活性。方法：利用软件对Alpha基因进行启动子预测；采用PCR 技术扩增出5 种不同长度的Alpha基因片段和正常TFEB基因启动子序列pTFEB ，构建含Alpha基因片段和pTFEB 的重组报告质粒；采用脂质体转染法将其分别转染至人胚肾293T 细胞；通过荧光素酶活性检测确定...
Alpha-1 Antitrypsin Deficiency in Iranian Patients with Chronic Obstructive Pulmonary Disease
Alpha-1 Antitrypsin Deficiency COPD Iran
2015/10/9
Background: Alpha-1 antitrypsin deficiency is a genetic disease which affects both lung and liver. This disease is a recognized factor for chronic obstructive pulmonary disease (COPD). However its imp...
Comparison of Alpha Blockers in Treatment of Premature Ejaculation: A Pilot Clinical Trial
Premature Ejaculation Quality of Life Serotonin Uptake Inhibitors
2015/10/9
Background:: Premature ejaculation (PE) is the most common sexual disorder in men and studies reported prevalence up to 30% (1, 2). PE is not a life-threatening medical condition but it influences the...