搜索结果: 1-15 共查到“医学 Actin”相关记录16条 . 查询时间(0.343 秒)
Megakaryocytes Regulate Expression of Pyk2 Isoforms and Caspase-mediated Cleavage of Actin in Osteoblasts
actin bone osteoblasts
2014/11/6
The proliferation and differentiation of osteoblast (OB) precursors are essential for elaborating the bone-forming activity of mature OBs. However, the mechanisms regulating OB proliferation and funct...
MCF-7细胞他莫昔芬耐药过程中F-actin细胞骨架的重构促进细胞迁移
乳腺癌 他莫昔芬 肌动蛋白 迁移
2013/11/14
研究人乳腺癌细胞MCF-7获得他莫昔芬(tamoxifen，TAM)耐药过程中发生的肌动蛋白细胞骨架重构及其对细胞迁移能力的影响，并探讨相关分子机制。 方法 采用高浓度短时间4-羟基他莫昔芬(4-hydroxytamoxifen，OHT)冲击法诱导人乳腺癌MCF-7/TAM耐药细胞株（Tam-R）。运用FITC标记的鬼笔环肽染色观察纤维状肌动蛋白（F-actin）动态变化，免疫...
观察诱发大鼠肝癌过程中PINCH1和F-actin蛋白表达特点，探讨其在肝癌发生发展过程中的作用。方法 利用二乙基亚硝胺(DEN)制备诱发性肝癌动物模型，采用免疫组织化学方法检测PINCH1和F-actin蛋白在对照组、模型Ⅰ组(6周)、模型Ⅱ组(14周)、模型Ⅲ组(22周)大鼠肝脏中表达的差异。结果 在对照组大鼠肝脏中少见PINCH1和F-actin蛋白表达阳性的细胞，其在模型Ⅰ组(6周)中主要...
CD2AP、F-actin在肾病大鼠中的表达及意义
CD2-associated protein 肾病 细胞骨架 微丝
2009/8/27
目的：观察CD2-associated protein（CD2AP）、肌动蛋白微丝（F-actin）在氨基核苷肾病大鼠肾小球中的表达变化及其意义。 方法： 通过建立大鼠氨基核苷肾病模型，采用免疫组织化学、蛋白质印迹技术观察CD2AP在不同时点肾病大鼠肾小球中的表达和分布变化，采用荧光技术检测肾小球F-actin含量的变化。 结果： ①肾小球足细胞CD2AP的表达在肾病模型建立的早期即有下调；在肾病...
Smooth Muscle Actin (SMA) Immunoreactivity in Primary Glomerulonephritis (GN)
Glomerulonephritis smooth muscle actin interstitium fibrosis
2009/6/29
The aims of this study were to determine the role of interstitial and glomerular myofibroblasts in the progression of various glomerulonephritis, and to assess the value of myofibroblasts in determini...
不同声强超声波对细胞骨架微丝F－actin表达的影响
不同声强超声波 细胞骨架微丝 F－actin表达
2009/6/17
目的：研究不同声强超声波对人脐血管内皮细胞（ECV-304）细胞骨架F-actin表达的影响，探讨超声波对人体的作用机制。 方法：将人脐血管内皮细胞ECV-304接种于6孔板中，分别以频率800kHz，占空比为30%功率密度0.20、0.40、0.60和0.80W/cm2，的脉冲超声波辐射5min，于辐射后不同时间，对ECV-304细胞进行F-actin免疫荧光染色，应用激光扫描共聚焦显微镜，观察...
整和素β1反义寡核甘酸对次声诱导ECV-304细胞F-actin表达的影响
整合素 寡核苷酸 次声 人脐静脉血管内皮细胞 聚合态肌动蛋白
2012/11/13
目的研究整合素β1反义寡核苷酸（ASODN）对次声诱导人脐血管内皮细胞（ECV-304）骨架微丝F-actin表达的影响，探讨次声信号向细胞内传导的途径。 方法应用脂质体转染试剂介导整合素β1正义寡核苷酸（SODN）和ASODN转染ECV-304，并将细胞分为次声假暴露组、次声假暴露+ASODN组（转染整合素β1反义寡核苷酸片断）、次声假暴露+SODN组（转染整合素β1正义寡核苷酸片断）、次声暴露...
目的： 采用人单核细胞株(THP-1)，建立小剂量BLP诱导THP-1细胞对BLP耐受的细胞模型，观察BLP诱导THP-1细胞对BLP耐受及对LPS交叉耐受时细胞actin骨架的变化情况，并探讨细胞actin骨架在BLP耐受及交叉耐受形成中的作用。方法: 采用人单核细胞株THP-1，建立小剂量BLP预处理诱导的BLP耐受细胞模型；采用ELISA法测定炎症因子TNF-α、IL-1β及IL-6浓度；采...
Micro/Nanoscale Biomechanics of Actin Stress Fibers.
Appearance of alpha-smooth muscle actin in peritubular cells of monkey testes is induced by androgens, modulated by follicle-stimulating hormone, and maintained after hormonal withdrawal
alpha-smooth muscle actin peritubular cells androgens follicle-stimulating hormone
2009/2/12
This study analyzed the hormonal requirements necessary for the development of primate testicular peritubular cells. Alpha-smooth muscle actin, as a specific differentiation marker for peritubular c...
目的：探讨4Hz／100dB、12Hz／100dB、20Hz／100dB的次声作用后，小鼠成骨样细胞MC3T3的细胞骨架F—actin表达的改变。方法：将MC3T3接种于细胞玻片上，并分为对照组和4Hz／100dB、12Hz／100dB、20Hz／100dB的次声暴露组。对照组无次声输出，其他各组接受次声作用30min／d。第3d于暴露后2h、4h、8h不同时间，对细胞进行F—actin的免疫荧光...
Actin and actin-binding proteins in bovine spermatozoa：potential role in membrane remodeling and intracellular signaling during epididymal maturation and the acrosome reaction
proteins bovine spermatozoa potential role signaling epididymal maturation
2008/12/26
The actin cytoskeleton influences a wide range of functions in nonmuscle somatic cells, including shape, movement, and interactions with extracellular matrices. The role of actin in mammalian male ger...
Glycerol disrupts tight junction-associated actin microfilaments, occludin, and microtubules in Sertoli cells
Glycerol disrupts tight junction-associated actin microfilaments occludin and microtubules in Sertoli cells
2008/12/25
Intratesticular injections of glycerol have been shown to result in a marked and prolonged reduction of spermatogenesis, accompanied by increased permeability of the blood-testis barrier. Because ...
An Ex Vivo Analysis of Sertoli Cell Actin Dynamics Following Gonadotropic Hormone Withdrawal
Espin profilin cofilin
2008/12/22
The receptors for the steroid hormone testosterone and the peptide hormone follicle-stimulating hormone are localized to the somatic Sertoli cell in the seminiferous epithelium. In the rat, prolonge...
期刊信息
篇名
Role of Rho kinase and actin filament in the increased vascular permeability of skin venule in rat after scalding.
语种
英文
撰写或编译
撰写
作者
Zheng HZh,Zhao KS,Zhou BY,Huang QB
第一作者单位
刊物名称
Burns
页面
200...